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Article
Open AccessDoes levonorgestrel-releasing intrauterine system increase breast cancer risk in peri-menopausal women? An HMO perspective
To evaluate the association between levonorgestrel-releasing intrauterine system (LNG-IUS) use and breast cancer (BC) risk.
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Article
Open AccessTrends in annual drug expenditure – a 16 year perspective of a public healthcare maintenance organization
Modern drug therapy accounts for a major share of health expenditure and challenges public provider resources. The objective of our study was to compare drug expenditure trends for ten major drug classes over ...
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Article
Potent CYP2D6 Inhibiting drugs do not increase relapse rate in early breast cancer patients treated with adjuvant tamoxifen
Endoxifen, the most active metabolite of the prodrug tamoxifen, is produced by cytochrome P450 CYP2D6. Breast cancer patients treated with tamoxifen who have reduced CYP2D6 activity, related to either genetic ...
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Article
A quantitative bioassay for nerve growth factor, using PC12 clones expressing different levels of trkA receptors
Nerve growth factor (NGF) is a neurotrophin required for differentiation, development, and survival of the sympathetic nervous system, with many of its biological effects being mediated via trkA receptors. The...