15 Result(s)
within
Isabelle Boccon-Gibod
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Article
Open AccessAndrogen transition and management of hereditary angioedema long-term prophylaxis in real life: a single-center case series
Hereditary angioedema (HAE) is a rare and potentially life-threatening disease that manifests clinically as recurrent episodes of swelling affecting multiple anatomical locations. Long-term prophylaxis (LTP) a...
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Article
Open AccessLong-term prophylaxis with lanadelumab for HAE: authorization for temporary use in France
Hereditary angioedema (HAE) is associated with a heavy burden of illness.
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Open AccessAttenuated androgen discontinuation in patients with hereditary angioedema: a commented case series
Hereditary angioedema (HAE) is characterized by potentially severe and life-threatening attacks of localized swelling. Prophylactic therapies are available, including attenuated androgens. Efficacy of attenuat...
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Article
Open AccessThe Global Registry for Hereditary Angioedema due to C1-Inhibitor Deficiency
Hereditary angioedema (HAE) is a rare condition, mostly due to genetic deficiency of complement C1 inhibitor (C1-INH). The rarity of HAE impedes extensive data collection and assessment of the impact of certai...
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Article
Efficacy of omalizumab for extracutaneous symptoms of chronic spontaneous urticaria
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Article
Hereditary Angioedema with and Without C1-Inhibitor Deficiency in Postmenopausal Women
Most types of hereditary angioedema (HAE) are worsened by endogenous or exogenous estrogens. Conversely, androgens can improve HAE with abnormal C1-Inhibitor (C1-INH) by increasing C1-INH concentrations. Menop...
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Article
Expert opinion: defining response to omalizumab in patients with chronic spontaneous urticaria
Omalizumab (a recombinant, humanized anti-immunoglobulin-E anti-body) has been shown in three pivotal Phase III trials (ASTERIA I, II and GLACIAL) and real-world studies to be effective and well-tolerated for ...
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Article
Open AccessAbstracts from the 10th C1-inhibitor deficiency workshop
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Article
Hereditary angioedema with normal C1 inhibitor: clinical characteristics and treatment response with plasma-derived human C1 inhibitor concentrate (Berinert®) in a French cohort
Hereditary angioedema (HAE) is a rare genetic disorder characterised by episodes of swelling without urticaria. Berinert® (CSL Behring) is a plasma-derived human C1 inhibitor (C1-INH) concentrate, approved for...
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Article
Idiopathic Non-histaminergic Angioedema: Successful Treatment with Omalizumab in Five Patients
Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease characterized by AE resistant to antihistamines and a chronic course. We report five new cases of InH-AAE (two women and three men) ...
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Article
Open AccessDedicated call center (SOS-HAE) for hereditary angioedema attacks: study protocol for a randomised controlled trial
Despite the availability of guidelines for the specific treatment of hereditary angioedema (HAE) attacks, HAE morbidity and mortality rates remain substantial. HAE attacks are a major medical issue requiring s...
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Article
Angioedema Triggered by Medication Blocking the Renin/Angiotensin System: Retrospective Study Using the French National Pharmacovigilance Database
Bradykinin-mediated angioedema (AE) is a rare side effect of some medications, including angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB). In France, side-effects to trea...
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Article
Towards a specific marker for acute bradykinin-mediated angioedema attacks: a literature review
Bradykinin-mediated angioedema (AE) is a rare disease characterised by recurrent angioedema linked to acquired (e.g. angiotensin converting enzyme inhibitor induced AE) or hereditary disorders (e.g. AE type I ...
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Article
Recurrent angioedema: diagnosis strategy and biological aspects
The aetiologies of recurrent angioedema (AE) comprise the frequent histaminergic AE and the rare bradykinin-mediated AE. Diagnosis must be done carefully because they do not have the same treatment. Diagnosis ...
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Article
Acquired C1-Inhibitor Deficiency: 7 Patients Treated with Rituximab
Acquired C1-inhibitor deficiency can occur secondary to excessive C1-inhibitor consumption (type I) and be associated with a lymphoid hemopathy, or linked to the presence of anti-C1–inhibitor autoantibodies (t...
