48 Result(s)
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Isabella Annesi-Maesano
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Open AccessMaternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed...
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Open AccessAnalysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
Seasonal variations in environmental exposures at birth or during gestation are associated with numerous adult traits and health outcomes later in life. Whether DNA methylation (DNAm) plays a role in the molec...
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Open AccessThe association between air pollution and the severity at diagnosis and progression of systemic sclerosis-associated interstitial lung disease: results from the retrospective ScleroPol study
To investigate the association of air pollution exposure with the severity of interstitial lung disease (ILD) at diagnosis and ILD progression among patients with systemic sclerosis (SSc)-associated ILD.
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Open AccessLongitudinal associations of DNA methylation and sleep in children: a meta-analysis
Sleep is important for healthy functioning in children. Numerous genetic and environmental factors, from conception onwards, may influence this phenotype. Epigenetic mechanisms such as DNA methylation have bee...
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Open AccessMeta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills
Cognitive skills are a strong predictor of a wide range of later life outcomes. Genetic and epigenetic associations across the genome explain some of the variation in general cognitive abilities in the general...
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Air Quality and Health Impacts
Associations between air pollution and overall morbidity and mortality have long been identified in Europe. Epidemiological studies have shown that there is an increased risk of cardiovascular and respiratory ...
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Open AccessThe association between environmental exposures to chlordanes, adiposity and diabetes-related features: a systematic review and meta-analysis
Chlordane compounds (CHLs) are components of technical chlordane listed in the Stockholm convention on persistent organic pollutants identified as endocrine disrupting chemicals (EDCs) and may interfere with h...
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Exposure to fine particulate matter and urticaria: an eco-epidemiological time-series analysis in Beirut
The association between ambient air pollution and several health conditions, including dermatologic disorders, has been heavily investigated. The mechanism involves an interplay of oxidative stress, inflammati...
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Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
Maternal anxiety during pregnancy is associated with adverse foetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered foetal DNA methylation (DNAm) has been proposed as a potenti...
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COVID-19 in Italy in the Context of the Pandemic Induced by SARS-Cov-2. Is There a Relationship Between COVID-19 and Atmospheric Air Pollution?
Following the outbreak of the disease in , was the first European country to be heavily involved in the defined as COVID-19 and induced by SARS-Cov-2 virus. During March 2020, many patients in the surroun...
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Open AccessDigital transformation of health and care to sustain Planetary Health: The MASK proof-of-concept for airway diseases—POLLAR symposium under the auspices of Finland’s Presidency of the EU, 2019 and MACVIA-France, Global Alliance against Chronic Respiratory Diseases (GARD, WH0) demonstration project, Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing
In December 2019, a conference entitled “Europe That Protects: Safeguarding Our Planet, Safeguarding Our Health” was held in Helsinki. It was co-organized by the Finnish Institute for Health and Welfare, the F...
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Open AccessEpigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated...
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Prevention of Allergic Asthma with Allergen Avoidance Measures and the Role of Exposome
It is well known that combination of sensitization and exposure to inhaled environmental allergens is related to both the development and elicitation of symptoms of asthma and that avoidance of allergens would...
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Open AccessIndoor exposure to particulate matter and volatile organic compounds in dwellings and workplaces and respiratory health in French farmers
Few investigations have related objective assessments of indoor air pollutants to respiratory health in farmers, in spite of the many rural environmental hazards to which they are exposed. Chemical air polluti...
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Open AccessNext-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases
In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support th...
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Open AccessMaternal diet before and during pregnancy and risk of asthma and allergic rhinitis in children
Consumption of certain foods during pregnancy has been shown to have beneficial effects on childhood asthma and allergic disease development and aggravation. However, most studies provide conflicting results a...
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Open AccessIs atopy a risk indicator of chronic obstructive pulmonary disease in dairy farmers?
Allergic mechanisms related to environmental and occupational exposure have been suggested to contribute to the development of chronic obstructive pulmonary disease (COPD).
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Open AccessThe clinical burden of allergic rhinitis in five Middle Eastern countries: results of the SNAPSHOT program
The SNAPSHOT program provides current data on the allergic rhinitis burden in the adult general population of five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia and the United Arab Emirates, th...
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Open AccessPOLLAR: Impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health (EIT Health) project
Allergic rhinitis (AR) is impacted by allergens and air pollution but interactions between air pollution, sleep and allergic diseases are insufficiently understood. POLLAR (Impact of air POLLution on sleep, As...
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Association Between Vitamin D Metabolism Gene Polymorphisms and Risk of Tunisian Adults’ Asthma
Several studies have shown a strong correlation between the serum vitamin D level and asthma severity and deficits in lung function.
