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Article
Open AccessRetinal capillary rarefaction in patients with untreated mild-moderate hypertension
Microvascular rarefaction influences peripheral vascular resistance, perfusion and metabolism by affecting blood pressure and flow pattern. In hypertension microvascular rarefaction has been described in exper...
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Article
Effects of linagliptin on renal endothelial function in patients with type 2 diabetes: a randomised clinical trial
Endothelial dysfunction predicts cardiovascular damage and renal involvement. Animal experiments and human studies indicate an increased nitric oxide (NO) activity and endothelial NO synthase (NOS) expression ...
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Article
Open AccessEffects of saxagliptin on early microvascular changes in patients with type 2 diabetes
Patients with diabetes mellitus are at increased risk for microvascular complications. Early changes in microcirculation are characterized by hyperperfusion (e.g. in the retina and kidney) and increased pulse ...
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Article
Towards a clinico-pathological classification of granule cell dispersion in human mesial temporal lobe epilepsies
The dentate gyrus (DG) plays a pivotal role in the functional and anatomical organization of the hippocampus and is involved in learning and memory formation. However, the impact of structural DG abnormalities...
