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Article
Open AccessLaboratory information management system for COVID-19 non-clinical efficacy trial data
As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus dis...
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Article
Open AccessThe collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2
C1q has been reported to reveal complement-independent roles in immune and non-immune cells. C1q binds to its specific receptors to regulate distinct functions that rely on the environment and cell types. Disc...
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Article
Open AccessHMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells
Although cellular senescence has emerged as a novel therapeutic concept in cancer, its underlying mechanisms remain unclear. High mobility group box 1 (HMGB1) and stimulator of interferon genes (STING) are inv...
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Article
Open AccessElectrical antimicrobial susceptibility testing based on aptamer-functionalized capacitance sensor array for clinical isolates
To prescribe effective antibiotics to patients with bacterial infections in a timely manner and to avoid the misuse of antibiotics, a rapid antimicrobial susceptibility test (AST) is essential. However, conven...
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Article
Open AccessDielectric imaging for differentiation between cancer and inflammation in vivo
In this study, we develop an in vivo dielectric imaging technique that measures capacitance using pin-type electrode arrays. Compared to normal tissues, cancer tissues exhibit higher capacitance values, allowing ...
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Article
Open AccessScreening of breast cancer stem cell inhibitors using a protein kinase inhibitor library
Cancer stem cells (CSCs), a subpopulation in tumors, are known to cause drug resistance, tumor recurrence and metastasis. Based on the characteristic formation of mammospheres in in vitro conditions, the mammo...
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Article
The Influence of Active Carbon Supports Toward the Electrocatalytic Behavior of Fe3O4 Nanoparticles for the Extended Energy Generation of Mediatorless Microbial Fuel Cells
Magnetite (Fe3O4) nanoparticles anchored over the different active carbon supports were developed by a simple wet solution method. The developed nanostructures were magnetically self-assembled over the electrode ...
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Article
Open AccessSublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model
Glioblastoma is a highly lethal neoplasm that frequently recurs locally after radiotherapy, and most of these recurrences originate from near the irradiated target field. In the present study, we identified th...
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Article
Open AccessConstitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state
With the increasing use of culture-expanded mesenchymal stromal cells (MSCs) for cell therapies, factors that regulate the cellular characteristics of MSCs have been of major interest. Oxygen concentration has...
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Article
Variants of BORIS minisatellites and relation to prognosis of prostate cancer
BORIS, a member of the cancer-testis antigen family with testis specific expression, showed abnormal expression in various cancer types including prostate cancer. In our previous work, we identified the polymorph...
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Article
Reformulation for Latent-Image Formation Model in Photolithography Using Numerical Absorbing Boundary Condition
A method for simulating latent image formation in a photoresist illuminated by an arbitrary imaging system is presented. A variational formulation for light scattering, which does not depend on a specific conf...
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Article
Catalytic and thermal degradation of Korean food sludge
Korean food waste sludge was degraded by using a new thermal degradation method. In this system, radish contained waste food sludge as main portion was selected as a standard material. Products of thermal degr...
