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Article
Open AccessSTING mediates nuclear PD-L1 targeting-induced senescence in cancer cells
Immune checkpoint molecule programmed death-ligand 1 (PD-L1) is overexpressed in cancer cells and imparts resistance to cancer therapy. Although membrane PD-L1 has been targeted for cancer immune therapy, nucl...
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Article
Open AccessThe collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2
C1q has been reported to reveal complement-independent roles in immune and non-immune cells. C1q binds to its specific receptors to regulate distinct functions that rely on the environment and cell types. Disc...
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Article
Audible sound-controlled spatiotemporal patterns in out-of-equilibrium systems
Naturally occurring spatiotemporal patterns typically have a predictable pattern design and are reproducible over several cycles. However, the patterns obtained from artificially designed out-of-equilibrium ch...
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Article
Relationship analysis of speech communication between salivary cortisol levels and personal characteristics using the Smartphone Linked Stress Measurement (SLSM)
Salivary cortisol is frequently used as a biomarker of stress. However, no study has used salivary cortisol to evaluate stress levels related to personal characteristics with a paper-based lateral flow assay (...
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Article
Signal amplification in a microfluidic paper-based analytical device (µ-PAD) by confinement of the fluidic flow
This is a one-step POC biosensor that guarantees rapid assay times, low-cost analysis, simple handling, stability, and is easy to mass product. However, it has several drawbacks such as limited sample volume a...
