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Article
Review of the potential pharmacological role of erucic acid: a monounsaturated omega-9 fatty acid
This comprehensive review aims to provide an overview of the pharmacological properties of erucic acid (EA) and highlight areas that require further research. EA is an omega-9 fatty acid found in certain veget...
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Article
Unwinding circular RNA’s role in inflammatory pulmonary diseases
Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and cellular processes in various physiological and pathological conditions. In recent years, there has been a growing interest in...
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Article
Polyphenol-Loaded Nano-carriers for Breast Cancer Therapy: A Comprehensive Review
Breast cancer remains a significant global health challenge, demanding innovative therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in fruits, vegetables, and beverages, poss...
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Article
Correction to: Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment
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Article
Therapeutic role of kaempferol and myricetin in streptozotocin-induced diabetes synergistically via modulation in pancreatic amylase, glycogen storage and insulin secretion
Kaempferol and Myricetin alone have promising benefits on diabetes and related complications, yet the effectiveness of cotreating the two compounds on diabetes have not been studied. The existing investigation...
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Article
Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment
Breast cancer is the most common cancer among women and is typically managed through surgery, radiation therapy, and chemotherapy. However, chemotherapy drugs often lack specificity, leading to various adverse...
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Chapter
Epigenetics of Influenza: The Host-Virus Interaction.
With advancements in science and technology, an equivalent growth in diseases has also been observed. A disease that has remained prevalent for decades, showing an almost incomparable persistence and adaptabil...
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Article
Molecular explanation of Wnt/βcatenin antagonist pyrvinium mediated calcium equilibrium changes in aging cardiovascular disorders
The symptoms of ageing are somewhat different and can lead to the altered role of the cardiovascular system at the levels of genetic, biochemical, tissue, organ, and systems. Ageing is an autonomous cardiovasc...
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Article
Sepsis triggered oxidative stress-inflammatory axis: the pathobiology of reprogramming in the normal sleep–wake cycle
In individuals with sepsis-related neurodegenerative illness, sleep and circadian rhythm disturbance are common. The alteration in genomic expression linked with the immune-directed oxidative stress-inflammato...
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Article
Open AccessIn-vitro and in-silico antibacterial activity of Azadirachta indica (Neem), methanolic extract, and identification of Beta.d-Mannofuranoside as a promising antibacterial agent
Antimicrobial resistance became the leading cause of death globally, resulting in an urgent need for the discovery of new, safe, and efficient antibacterial agents. Compounds derived from plants can provide an...
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Article
Nanocrystals: Characterization Overview, Applications in Drug Delivery, and Their Toxicity Concerns
Nanocrystals (NCs) are the class of solid dosage forms which utilizes the concept of nanoscience together with crystal nature of drug to achieve advantages in terms of solubility, dissolution, and physicochemi...
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Article
Anti-Huntington’s Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action
Butin has a strong antioxidant plus anti-inflammatory action and it is reported to be protective in oxidative stress-induced mitochondrial dysfunction. Butin has been shown to protect the mouse hippocampus HT2...
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Article
Methanolic extract of Cucumis melo attenuates ethylene glycol-induced nephrolithiasis in Wistar rats
Evaluation of the effects of methanolic extract of Cucumis melo in ethylene glycol-induced nephrolithiasis on Wistar rats. 0.75% solution of ethylene glycol (EG) in payable water was given to produce nephrolithia...
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Article
Potential of Natural Bioactive Compounds in Management of Diabetes: Review of Preclinical and Clinical Evidence
Diabetes is one of the most common metabolic disorders often associated with hyperglycemia, altered carbohydrate, lipid, and protein metabolism. Type 2 diabetes is the most common type of diabetes associated w...
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Article
Open AccessScale-up fermentation of Escherichia coli for the production of recombinant endoglucanase from Clostridium thermocellum
Endoglucanase (EC 3.2.1.4) catalysing the hydrolysis of β-1.4-glycosidic linkage of cellulose molecules is an enzyme of tremendous industrial importance. The present study describes a response surface methodol...
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Article
Biochemical interaction of salt sensitivity: a key player for the development of essential hypertension
Worldwide, more than 1 billion people have elevated blood pressure, with up to 45% of adults affected by the disease. In 2016 the global health study report on patients from 67 countries was released in Lancet...
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Article
Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway
Carfilzomib (CFZ), a proteasome inhibitor approved by the FDA to treat multiple myeloma, may cause nephrotoxicity.
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Article
Antineoplastic influence of nimesulide in chemically induced hepatocellular carcinoma by inhibition of DNA synthesis
Hepatocellular carcinoma is emerging as one of the most common forms of cancer resulting in thousands of death worldwide. The purpose of this study was to screen nimesulide for anticancer activity in chemicall...
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Chapter
Dietary Phytochemicals and Their Potential Effects on Diabetes Mellitus 2
Type 2 diabetes mellitus (T2DM) is one of the most important contemporary medical problems that exceed 200 million worldwide. T2DM causes increased risks of cardiovascular disease, kidney failure, blindness, n...
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Chapter
Medicinal Plants in the Treatment of Arthritis
Arthritis is an inflammatory, chronic, autoimmune disorder identified by swelling, stiffness, and pain. It covers 0.5% of population of the world and leads to disability in joint. Synthetic drugs are used to t...
