Skip to main content

and
Your search also matched 36 preview-only Content is preview-only when you or your institution have not yet subscribed to it.

By making our abstracts and previews universally accessible we help you purchase only the content that is relevant to you.
results, e.g.

Biopsy remains indispensable for evaluating bone marrow involvement in DLBCL patients despite the use of positron emission tomography

Include preview-only content
  1. Article

    Open Access

    An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development

    The BTBR T+Itpr3tf/J (BTBR/J) strain is one of the most valid models of idiopathic autism, serving as a potent forward genetics tool to dissect the complexity of autism. We found that a sister strain with an inta...

    Chia-Wen Lin, Jacob Ellegood, Kota Tamada, Ikuo Miura, Mikiko Konda in Molecular Psychiatry (2023)

  2. Article

    Open Access

    Sex-linked markers in an Australian frog Platyplectrum ornatum (Limnodynastidae) with a small genome and homomorphic sex chromosomes

    Amphibians have highly diverse sex-determining modes leading to a notable interest in vertebrate sex determination and sex chromosome evolution. The identification of sex-determining systems in amphibians, how...

    Chad Schimek, Foyez Shams, Ikuo Miura, Simon Clulow, Zuzana Majtanova in Scientific Reports (2022)

  3. Article

    Publisher Correction: Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Shinya Tanaka, Wataru Ise, Takeshi Inoue, Ayako Ito, Chisato Ono in Nature Immunology (2020)

  4. Article

    Open Access

    A rapid rate of sex-chromosome turnover and non-random transitions in true frogs

    The canonical model of sex-chromosome evolution predicts that, as recombination is suppressed along sex chromosomes, gametologs will progressively differentiate, eventually becoming heteromorphic. However, the...

    Daniel L. Jeffries, Guillaume Lavanchy, Roberto Sermier in Nature Communications (2018)

  5. Article

    Correction to: Cell dynamics during differentiation therapy with all-trans retinoic acid in acute promyelocytic leukemia

    In the original publication of the article, Table 2 was published incorrectly. The column names were swapped under the column heading “Prom (%)”. The correct column names are PB and BM.

    Kazuyuki Sato, Hirotaka Sakai, Yusuke Saiki in International Journal of Hematology (2018)

  6. Article

    Open Access

    Genetic map** of a male factor subfertility locus on mouse chromosome 4

    Male reproductive anomalies are widely distributed among mammals, and male factors are estimated to contribute to approximately 50% of cases of human infertility. The B10.M/Sgn (B10.M) mouse strain exhibits tw...

    Hideo Gotoh, Ikuo Miura, Shigeharu Wakana in Mammalian Genome (2018)

  7. Article

    Open Access

    A portion of expanded granular lymphocytes cause pure white cell aplasia?

    Yasushi Isobe, Yu Uemura, Akiko Uchida, Ikuo Miura in Annals of Hematology (2018)

  8. Article

    Open Access

    De novo acute lymphoblastic leukemia-like disease of high grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a case report and literature review

    B-cell lymphomas harboring the 8q24/MYC plus 18q21/BCL2 translocations are now referred to as high grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-MBR). Although HGBL-MBR is frequently fo...

    Akiko Uchida, Yasushi Isobe, Yu Uemura, Yuji Nishio in BMC Clinical Pathology (2017)

  9. Article

    Open Access

    The parathyroid hormone regulates skin tumour susceptibility in mice

    Using a forward genetics approach to map loci in a mouse skin cancer model, we previously identified a genetic locus, Skin tumour modifier of MSM 1 (Stmm1) on chromosome 7, conferring strong tumour resistance. Su...

    Kazuhiro Okumura, Megumi Saito, Yasuhiro Yoshizawa, Haruka Munakata in Scientific Reports (2017)

  10. Article

    Open Access

    Phylogeography reveals an ancient cryptic radiation in East-Asian tree frogs (Hyla japonica group) and complex relationships between continental and island lineages

    In contrast to the Western Palearctic and Nearctic biogeographic regions, the phylogeography of Eastern-Palearctic terrestrial vertebrates has received relatively little attention. In East Asia, tectonic event...

    Christophe Dufresnes, Spartak N. Litvinchuk, Amaël Borzée in BMC Evolutionary Biology (2016)

  11. Article

    Open Access

    Identification of mutations through dominant screening for obesity using C57BL/6 substrains

    The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has b...

    Mohammad Sarowar Hossain, Fuyuki Asano, Tomoyuki Fujiyama in Scientific Reports (2016)

  12. Article

    Open Access

    KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR

    KDEL receptors are responsible for retrotransporting endoplasmic reticulum (ER) chaperones from the Golgi complex to the ER. Here we describe a role for KDEL receptor 1 (KDELR1) that involves the regulation of...

    Daisuke Kamimura, Kokichi Katsunuma, Yasunobu Arima, Toru Atsumi in Nature Communications (2015)

  13. Article

    Open Access

    Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice

    Disrupted-in-schizophrenia 1 (DISC1) is a promising candidate susceptibility gene for psychiatric disorders, including schizophrenia, bipolar disorder and major depression. Several previous studies reported th...

    Yosefu Arime, Ryutaro Fukumura, Ikuo Miura in Behavioral and Brain Functions (2014)

  14. Article

    Open Access

    The evolution of mitochondrial genomes in modern frogs (Neobatrachia): nonadaptive evolution of mitochondrial genome reorganization

    Although mitochondrial (mt) gene order is highly conserved among vertebrates, widespread gene rearrangements occur in anurans, especially in neobatrachians. Protein coding genes in the mitogenome experience ad...

    Yun **a, Yuchi Zheng, Ikuo Miura, Pamela BY Wong, Robert W Murphy in BMC Genomics (2014)

  15. Article

    Open Access

    QTL on mouse chromosomes 1 and 4 causing sperm-head morphological abnormality and male subfertility

    The B10.M mouse strain represents a model for male subfertility as it produces a significantly low number of offspring. The only known male reproductive phenotype of this strain is its high frequency of sperm-...

    Hideo Gotoh, Keitaro Hirawatari, Naoto Hanzawa, Ikuo Miura in Mammalian Genome (2012)

  16. Article

    Independent degeneration of W and Y sex chromosomes in frog Rana rugosa

    The frog Rana rugosa uniquely possesses two different sex-determining systems of XX/XY and ZZ/ZW, separately in the geographic populations. The sex chromosomes of both types share the same origin at chromosome 7,...

    Ikuo Miura, Hiromi Ohtani, Mitsuaki Ogata in Chromosome Research (2012)

  17. Article

    Open Access

    Primary splenic diffuse large B-cell lymphoma manifesting in red pulp

    We evaluated six cases of diffuse large B-cell lymphoma (DLBCL) involving the red pulp of the spleen. All had B symptoms and an aggressive clinical course. The lymphoma cells proliferated diffusely and non-coh...

    Makoto Kashimura, Masahiro Noro, Bunshiro Akikusa, Atsushi Okuhara in Virchows Archiv (2008)

  18. Article

    Open Access

    Disentangling genetic vs. environmental causes of sex determination in the common frog, Rana temporaria

    Understanding of sex ratio dynamics in a given species requires understanding its sex determination system, as well as access for reliable tools for sex identification at different life stages. As in the case ...

    Chikako Matsuba, Ikuo Miura, Juha Merilä in BMC Genetics (2008)