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A Cascade of epistatic interactions regulating teratozoospermia in mice

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  1. Article

    Open Access

    Genetic map** of a male factor subfertility locus on mouse chromosome 4

    Male reproductive anomalies are widely distributed among mammals, and male factors are estimated to contribute to approximately 50% of cases of human infertility. The B10.M/Sgn (B10.M) mouse strain exhibits tw...

    Hideo Gotoh, Ikuo Miura, Shigeharu Wakana in Mammalian Genome (2018)

  2. Article

    Open Access

    The evolution of mitochondrial genomes in modern frogs (Neobatrachia): nonadaptive evolution of mitochondrial genome reorganization

    Although mitochondrial (mt) gene order is highly conserved among vertebrates, widespread gene rearrangements occur in anurans, especially in neobatrachians. Protein coding genes in the mitogenome experience ad...

    Yun **a, Yuchi Zheng, Ikuo Miura, Pamela BY Wong, Robert W Murphy in BMC Genomics (2014)

  3. Article

    Open Access

    QTL on mouse chromosomes 1 and 4 causing sperm-head morphological abnormality and male subfertility

    The B10.M mouse strain represents a model for male subfertility as it produces a significantly low number of offspring. The only known male reproductive phenotype of this strain is its high frequency of sperm-...

    Hideo Gotoh, Keitaro Hirawatari, Naoto Hanzawa, Ikuo Miura in Mammalian Genome (2012)

  4. Article

    Independent degeneration of W and Y sex chromosomes in frog Rana rugosa

    The frog Rana rugosa uniquely possesses two different sex-determining systems of XX/XY and ZZ/ZW, separately in the geographic populations. The sex chromosomes of both types share the same origin at chromosome 7,...

    Ikuo Miura, Hiromi Ohtani, Mitsuaki Ogata in Chromosome Research (2012)

  5. Article

    Open Access

    Disentangling genetic vs. environmental causes of sex determination in the common frog, Rana temporaria

    Understanding of sex ratio dynamics in a given species requires understanding its sex determination system, as well as access for reliable tools for sex identification at different life stages. As in the case ...

    Chikako Matsuba, Ikuo Miura, Juha Merilä in BMC Genetics (2008)