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Article
Open AccessImpact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet
We previously reported the neuroprotective potential of combined hydrogen (H2) gas ventilation therapy and therapeutic hypothermia (TH) by assessing the short-term neurological outcomes and histological findings ...
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Article
Open Accessp62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis
The autophagy–lysosome pathway and apoptosis constitute vital determinants of cell fate and engage in a complex interplay in both physiological and pathological conditions. Central to this interplay is the arc...
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Article
Open AccessCerebral hemodynamics during neonatal transition according to mode of delivery
Cerebral haemodynamics during the immediate transition period in neonates may differ depending on whether delivery is vaginal or by caesarean section. However, these differences have never been confirmed by ne...
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Chapter
The Impacts of Salmonella Infection on Human Cancer
Non-typhoidal Salmonella enterica is the leading cause of foodborne illnesses resulting over 153 million of incidence per year worldwide, while typhoidal Salmonella infection disproportionally affects low- to mid...
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Article
Open AccessVariations in cag pathogenicity island genes of Helicobacter pylori from Latin American groups may influence neoplastic progression to gastric cancer
Helicobacter pylori (HP) colonizes the human stomach and induces acute gastritis, peptic ulcer disease, atrophic gastritis, and gastric adenocarcinoma. Increased virulence in HP isolates derives from harboring th...
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Article
Open AccessAntibody responses to flagellin C and Streptococcus gallolyticus pilus proteins in colorectal cancer
Antibodies to Streptococcus gallolyticus subspecies gallolyticus (SGG) have been associated with colorectal cancer (CRC). Because SGG may correlate with impaired gut epithelia, we assessed the association of anti...
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Article
Open AccessHydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model
Despite its poor outcomes, therapeutic hypothermia (TH) is the current standard treatment for neonatal hypoxic-ischaemic encephalopathy (HIE). In this study, due to its antioxidant, anti-inflammatory, and anti...
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Article
Open AccessThe accuracy of chemotherapy ascertainment among colorectal cancer patients in the surveillance, epidemiology, and end results registry program
Surveillance, Epidemiology, and End Results (SEER) public research database does not include chemotherapy data due to concerns for incomplete ascertainment. To compensate for perceived lack of data quality man...
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Chapter
Oral Microbiome: Potential Link to Systemic Diseases and Oral Cancer
The human oral microbiome comprises more than 2,000 bacterial taxa, including a large number of opportunistic pathogens, and it is considered to be the second most diverse microbial community following stool. ...
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Article
Differential effects of patient-related factors on the outcome of radiation therapy for rectal cancer
The objective of this study was to investigate whether cancer-specific survival in rectal cancer patients is affected by patient-related factors, conditional on radiation treatment.
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Article
Markers of systemic exposures to products of intestinal bacteria in a dietary intervention study
Systemic exposures to intestinal bacteria may play a role in the etiology of the chronic, low-grade inflammation that is associated with western diets. Production of lipopolysaccharide-binding protein (LBP) i...
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Article
Fecal Biomarkers for Research on Dietary and Lifestyle Risk Factors in Colorectal Cancer Etiology
Stool, consisting of undigested food, endogenous secretions, and microbiota and exfoliated host cellular components, is an ideal biospecimen for non-invasive evaluation of the whole bowel environment regarding...
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Article
Unmet adolescent and young adult cancer survivors information and service needs: a population-based cancer registry study
We described unmet information and service needs of adolescent and young adult (AYA) cancer survivors (15–39 years of age) and identified sociodemographic and health-related factors associated with these unmet...
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Chapter
Streptococcus bovis and Colorectal Cancer
The most salient feature of Streptococcus bovis (SB) is its clinical association with malignancy of the colon and rectum. The relationship between SB and colorectal cancer (CRC) was already recognized in the 1950...
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Article
Hemodynamic Changes in the Breast and Frontal Cortex of Mothers During Breastfeeding
The objective of this study was to confirm physiological reactions in the breast and brain in mothers during breastfeeding and collect basic objective data, aiming at effective support for breastfeeding. Ten h...
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Article
Open AccessRecruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE Study
Cancer is rare in adolescents and young adults (AYA), but these patients have seen little improvement in survival in contrast to most other age groups. Furthermore, participation in research by AYAs is typical...
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Article
Functional Lateralization of Sensorimotor Cortex in Infants Measured Using Multichannel Near-Infrared Spectroscopy
Multichannel near-infrared spectroscopy (MNIRS) was used for the functional imaging of the sensorimotor cortex of newborn infants during passive knee and elbow movement under sedated sleep. Contralateral knee ...
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Article
Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies
To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer.
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Article
Polymorphisms in Genes Related to Bacterial Lipopolysaccharide/Peptidoglycan Signaling and Gastric Precancerous Lesions in a Population at High Risk for Gastric Cancer
As Helicobacter pylori (HP) is a Gram-negative bacterium, we investigated the associations between several functional polymorphisms in genes involved in lipopolysaccharide (LPS) signaling and the prevalence of va...
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Article
Genetic polymorphisms in anti-inflammatory cytokine signaling and the prevalence of gastric precancerous lesions in Venezuela
The aim of the study was to assess the effects of genetic polymorphisms in anti-inflammatory mediators, i.e., IL10, IL4 and IL4R on the prevalence of gastric precancerous lesions and their interactions with other...
