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  1. No Access

    Article

    Primary cemiplimab treatment for orbital squamous cell carcinoma is effective and may alleviate the need for orbital exenteration

    To evaluate the effectiveness of cemiplimab, a Programmed-cell-death-1(PD-1) protein inhibitor, for the treatment of cutaneous periocular-locally-advanced squamous-cell-carcinoma (POLA-SCC) with orbital-invasion.

    Alon Tiosano, Meydan Ben-Ishai, Yaacov Cnaany, Gal Markel, Noga Kurman… in Eye (2023)

  2. No Access

    Article

    The initial rate of tumour response to vismodegib treatment, can predict a complete response outcome for periocular LA-BCC

    To establish a model to predict treatment outcome of periocular locally advanced basal cell carcinoma (POLA BCC) based on initial response to treatment with vismodegib (ErivedgeTM), a sonic hedgehog inhibitor.

    Alon Tiosano, Meydan Ben-Ishai, Eyal Fenig, Guy J. Ben simon, Iftach Yassur in Eye (2023)

  3. No Access

    Article

    Vismodegib improves quality of life in patients with periocular locally advanced basal cell carcinoma: subgroup analysis, STEVIE trial

    To evaluate the effect of locally advanced periocular basal cell carcinoma (POLA-BCC) on health-related quality of life (HRQoL) and the benefit of vismodegib treatment among participants in the Safety Events i...

    Assaf Gershoni, Alon Tiosano, Meydan Ben Ishai, Edward Barayev, Guy J. Ben Simon… in Eye (2022)

  4. No Access

    Reference Work Entry In depth

    Periocular Basal Cell Carcinoma (BCC)

  5. BCC is the most common eyelid malignancy, accounting for over 90% of malignant eyelid neoplasms.

  6. Risk factors...

    7. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging (2022)

  7. No Access

    Reference Work Entry In depth

    Periocular Sebaceous Cell Carcinoma

  8. Lesions usually originate from the sebaceous glands including meibomian glands and the Zeis glands.

  9. May prese...

    10. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging (2022)

  10. No Access

    Reference Work Entry In depth

    Periocular Squamous Cell Carcinoma (SCC)

  11. Lesions usually originate from the skin of the eyelids, eyebrow, or canthal region.

  12. May present as a well-def...

    13. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging (2022)

  13. No Access

    Article

    Trametinib for orbital plexiform neurofibromas in young children with neurofibromatosis type 1

    Plexiform neurofibromas (PNF) in neurofibromatosis type 1 (NF1) are usually diagnosed in childhood and can grow rapidly during this period. In 10% of patients, PNF involve the orbital-periorbital area and may ...

    Helen Toledano, Gad Dotan, Rivka Friedland, Rony Cohen… in Child's Nervous System (2021)

  14. No Access

    Living Reference Work Entry In depth

    Periocular Sebaceous Cell Carcinoma

  15. Lesions usually originate from the sebaceous glands including meibomian glands and the Zeis glands.

  16. May present as a well...

    17. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging

  17. No Access

    Living Reference Work Entry In depth

    Periocular Squamous Cell Carcinoma (SCC)

  18. Lesions usually originate from the skin of the eyelids, eyebrow, or canthal region.

  19. May present as a well-defined exophyt...

    20. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging

  20. No Access

    Living Reference Work Entry In depth

    Periocular Basal Cell Carcinoma (BCC)

  21. BCC is the most common eyelid malignancy, accounting for over 90% of malignant eyelid neoplasms.

  22. Risk factors: lightly pi...

    23. Alon Tiosano, Natalia Michaeli, Iftach Yassur in Atlas of Orbital Imaging

  23. Article

    Open Access

    Gene-Related Response of Basal Cell Carcinoma to Biologic Treatment with Vismodegib

    We aimed to characterise the response of locally advanced basal cell carcinoma (BCC) to systemic treatment with Vismodegib, a Hedgehog pathway inhibitor, by changes in the expression levels of Hedgehog pathway...

    Amir Sternfeld, Shirel Rosenwasser-Weiss, Gur Ben-Yehuda… in Scientific Reports (2020)

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