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Open AccessInsights into treatment of complex Crohn's perianal fistulas
Complex perianal fistula is a common complication of Crohn’s disease (CD) which leads to negative impact on patient’s quality of life. Successful management of the disease requires a multidisciplinary approach...
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Open AccessResponse to Limited surface impacts of the January 2021 sudden stratospheric warming
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Open AccessA comparison of covariate adjustment approaches under model misspecification in individually randomized trials
Adjustment for baseline covariates in randomized trials has been shown to lead to gains in power and can protect against chance imbalances in covariates. For continuous covariates, there is a risk that the the...
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Open AccessDemonstration of high-speed and low-complexity continuous variable quantum key distribution system with local local oscillator
We present an experimental demonstration of the feasibility of the first 20 + Mb/s Gaussian modulated coherent state continuous variable quantum key distribution system with a locally generated local oscillato...
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Open AccessDiet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice
Obesity is one of the largest modifiable risk factors for the development of musculoskeletal diseases, including intervertebral disc (IVD) degeneration and back pain. Despite the clinical association, no studi...
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Open AccessExperimental demonstration of single-shot quantum and classical signal transmission on single wavelength optical pulse
Advances in highly sensitive detection techniques for classical coherent communication systems have reduced the received signal power requirements to a few photons per bit. At this level one can take advantage...
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Open AccessOne-year anniversary: The progress of Microsystems & Nanoengineering
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Open AccessHandling drop-outs which imply a change of treatment: an evaluation of reference-based imputation
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Open AccessThe First Engineering Journal from Nature Publishing Group: Microsystems & Nanoengineering
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Open AccessAdjusting for treatment changes in epilepsy: causal analysis of randomised controlled trial survival outcomes in the presence of departure from randomised treatment
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Regional Assessment of Oceania
Oceania is defined by the United Nations as the islands within Polynesia, Micronesia and Melanesia, Australia and New Zealand. The islands in the Pacific Ocean were urbanized relatively recently (typically fol...
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Open AccessDeparture from treatment protocol in published randomised controlled trials: a review
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No vote ‐ no census: an account of some of the events of 1910–1911
The 2011 Census on the 27 March will be the latest in a series spanning over two centuries and covering vast demographic changes in the British population. Although the underlying aim of each census since 1801...
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The 2011 Census taking shape: methodological and technological developments
As reported in Population Trends 1351 the UK Statistics Authority’s proposals for the next Census in England and Wales, to be taken in March 2011, were published and presented to Parliament and the National Assem...
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The 2011 Census taking shape: the selection of topics and questions
The UK Statistics Authority’s proposals for the next census in England and Wales, to be taken in March 2011, were published and presented to Parliament and the National Assembly for Wales in a Government White...
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Article
Open AccessLongitudinal variance-components analysis of the Framingham Heart Study data
The Framingham Heart Study offspring cohort, a complex data set with irregularly spaced longitudinal phenotype data, was made available as part of Genetic Analysis Workshop 13. To allow an analysis of all of t...
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Book Reviews
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Outcomes analysis can provide new directions for the management of patients undergoing lumbar spine surgery
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Article
Inadvertent epidural administration of potassium chloride
A 24-year-old black female presented for repeat elective Caesarean section. The procedure was performed under epidural anaesthesia. Sufentanil 25 μg, intended for postoperative analgesia, was inadvertently dil...
