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  1. No Access

    Article

    Optimierung der 223Radium-Dichlorid-Therapie von Patienten mit kastrationsresistentem Prostatakarzinom und Knochenmetastasen

    223Radium(Ra)-Dichlorid (Radium-223, Xofigo®, Bayer AG, Leverkusen) ist die erste gezielte Alphastrahler-Therapie zur Verlängerung des Überlebens bei erwachsenen Patienten mit kastrationsresistentem Prostatakarzi...

    PD Dr. H. Ilhan, L. Stegger, M. Dietlein, M.-O. Möllers… in best practice onkologie (2021)

  2. No Access

    Article

    Factors Influencing Longitudinal Stair Climb Performance from Midlife to Early Late Life: The Study of Women’s Health Across the Nation Chicago and Michigan Sites

    To quantify the longitudinal change in stair climb performance (a measure indicative of both physical function and muscle power), determine whether physical activity is related to slower decline in performance...

    Brittney S. Lange-Maia… in The journal of nutrition, health & aging (2019)

  3. Article

    Open Access

    Imputing accelerometer nonwear time in children influences estimates of sedentary time and its associations with cardiometabolic risk

    A limitation of measuring sedentary time with an accelerometer is device removal. The resulting nonwear time is typically deleted from the data prior to calculating sedentary time. This could impact estimates ...

    M. M. Borghese, E. Borgundvaag… in International Journal of Behavioral Nutrit… (2019)

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  4. No Access

    Article

    Rheumatoide Arthritis der zervikalen Wirbelsäule

    Neben dem Befall der kleinen peripheren Gelenke gilt die Halswirbelsäule als die am zweithäufigsten betroffene Körperregion einer rheumatoiden Arthritis. Zurückzuführen auf eine Verbesserung der medikamentösen...

    I. Janssen, E. Shiban, B. Meyer in Zeitschrift für Rheumatologie (2018)

  5. Article

    Open Access

    Occupational and leisure time physical inactivity and the risk of type II diabetes and hypertension among Mexican adults: A prospective cohort study

    There is a lack of longitudinal data linking physical inactivity and chronic diseases among Mexicans. Objective. To examine the relationship between total, leisure and occupational moderate-to-vigorous physical a...

    C. Medina, I. Janssen, S. Barquera, S. Bautista-Arredondo… in Scientific Reports (2018)

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  6. No Access

    Article

    Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese women

    Telomere length can be considered as a biological marker for cell proliferation and aging. Obesity is associated with adipocyte hypertrophy and proliferation as well as with shorter telomeres in adipose tissue...

    F el Bouazzaoui, P Henneman, P Thijssen, A Visser… in International Journal of Obesity (2014)

  7. No Access

    Article

    Präoperative und intraoperative Funktionslokalisierung bei eloquenten Metastasen

    Die Etablierung von präoperativer Kartierung mittels navigierter transkranieller Magnetstimulation (nTMS) sowie des intraoperativen Neuromonitorings (IONM) mithilfe motorisch evozierter Potenziale (MEP) erlaub...

    S.M. Krieg, T. Obermüller, I. Janssen, C. Negwer, F. Ringel… in Der Onkologe (2014)

  8. No Access

    Article

    Preventieve screening bij jeugdige basketballers

    De sportpodotherapeut wordt regelmatig, met succes, ingeschakeld bij het behandelen van sportblessures. Naast het behandelen van blessures lijkt er ook een grote rol weggelegd in de preventieve begeleiding van...

    I. Janssen, N. Liem in PodoSophia (2011)

  9. No Access

    Article

    Sarcopenic-obesity and cardiovascular disease risk in the elderly

    To determine: 1) whether sarcopenic-obesity is a stronger predictor of cardiovascular disease (CVD) than either sarcopenia or obesity alone in the elderly, and 2) whether muscle mass or muscular strength is a ...

    W. C. Stephen, I. Janssen in JNHA - The Journal of Nutrition, Health and Aging (2009)

  10. No Access

    Article

    Separate and combined influence of body mass index and waist circumference on arthritis and knee osteoarthritis

    To determine if the combination of body mass index (BMI) and waist circumference (WC) explains an additional component of arthritis and knee osteoarthritis risk than is accounted for by either anthropometric m...

    I Janssen, A E Mark in International Journal of Obesity (2006)

  11. No Access

    Chapter and Conference Paper

    Cognitive epidemiology: psychological and social risk mechanisms for psychosis

    The hypothesis that psychosis exists in nature as a distribution of symptoms is not so bold as it may seem [1]. For example, in the case of depression, both genetic and community studies suggest that the phenotyp...

    J. Van Os, I. Janssen, M. Hanssen, M. Bak… in Risk and Protective Factors in Schizophren… (2002)

  12. No Access

    Article

    Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain

    Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) lower the risk of develo** Alzheimer's disease (AD). Most NSAIDs act upon local inflammatory events by inhibiting the expr...

    J. J. M. Hoozemans, A. J. M. Rozemuller, I. Janssen… in Acta Neuropathologica (2001)

  13. No Access

    Article

    Effects of sex on the change in visceral, subcutaneous adipose tissue and skeletal muscle in response to weight loss

    OBJECTIVE: To examine the influence of sex on whole body and regional subcutaneous, visceral, total adipose tissue (AT), skeletal muscle (SM), and lean tissue in response to weight loss induced by diet alone (...

    I Janssen, R Ross in International Journal of Obesity (1999)

  14. No Access

    Article

    Complement C1-inhibitor expression in Alzheimer’s disease

    In situ and in vitro studies suggest that activation of locally produced complement factors may act as a mediator between amyloid deposits and neurodegenerative changes seen in Alzheimer’s disease (AD). C1-es...

    R. Veerhuis, I. Janssen, J. J. M. Hoozemans, C. J. A. De Groot… in Acta Neuropathologica (1998)

  15. No Access

    Article

    Early complement components in Alzheimer's disease brains

    Activation products of the early complement components C1, C4 and C3 can be found colocalized with diffuse and fibrillar β-amyloid (β/A4) deposits in Alzheimer's disease (AD) brains. Immunohistochemically, C1...

    R. Veerhuis, I. Janssen, C.E. Hack, P. Eikelenboom in Acta Neuropathologica (1995)

  16. No Access

    Article

    Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3

    In Alzheimer's disease (AD) patients, the complement components Clq, C4 and C3 can be detected in different types of β/A4 plaques, one of the hallmarks of AD. Contradictory findings on the presence of late com...

    R. Veerhuis, P. van der Valk, I. Janssen, S. S. Zhan, P. Eikelenboom… in Virchows Archiv (1995)