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Article
Open AccessThe new insight into the inflammatory response following focused ultrasound-mediated blood–brain barrier disruption
Despite the great potential of FUS-BBB disruption (FUS-BBBD), it is still controversial whether FUS-BBBD acts as an inducing factor of neuro-inflammation or not, and the biological responses after FUS-BBBD tri...
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Article
Pilot study of a single-channel EEG seizure detection algorithm using machine learning
Seizures are one of the most common emergencies in the neonatal intensive care unit (NICU). They are identified through visual inspection of electroencephalography (EEG) reports and treated by neurophysiologic...
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Article
Open AccessA local difference in blood–brain barrier permeability in the caudate putamen and thalamus of a rat brain induced by focused ultrasound
A blood–brain barrier (BBB) opening induced by focused ultrasound (FUS) has been widely studied as an effective way of treating brain diseases. We investigate the effect of ultrasound’s incidence angle at caudate...
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Article
Open AccessThe Effect of a Transcranial Channel as a Skull/Brain Interface in High-Definition Transcranial Direct Current Stimulation—A Computational Study
A transcranial channel is an interface between the skull and brain; it consists of a biocompatible and highly conductive material that helps convey the current induced by transcranial direct current stimulatio...
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Article
Open AccessEffect of Anatomically Realistic Full-Head Model on Activation of Cortical Neurons in Subdural Cortical Stimulation—A Computational Study
Electrical brain stimulation (EBS) is an emerging therapy for the treatment of neurological disorders and computational modeling studies of EBS have been used to determine the optimal parameters for highly cos...
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Article
E-CoCS: Environment of computational simulator for cortical stimulation
Subdural cortical stimulation is known to be useful in treating brain disorders by injection of electrical current through electrodes beneath the dura matter. However, due to huge experimental cost, it has bee...
