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Article
Solitary plasmacytoma of bone and extramedullary plasmacytoma
Among plasma cell disorders, solitary plasmacytoma (solitary-plasmacytoma of bone, SPB and extramedullary plasmacytoma, EMP) is rare as compared with mulitiple myeloma (MM). Furthermore, the relationship betwe...
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Article
Risk factors and prognosis of surgery for spinal metastasis
To evaluate the risk factors and prognosis of surgery for spinal metastasis.
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Article
Preparation and activity of a nanometer anti-microbial polyurethane
A novel way for photo-immobilization with interferon- α (IFN- α) on the surface of polyurethane (PU) material, which makes PU condom more effective function in the future, was investigated. A kind of photoactive ...
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Article
Valgus osteotomy in combination with dynamic hip screw fixation for fibrous dysplasia with shepherd’s crook deformity
The treatment of fibrous dysplasia with shepherd’s crook deformity is a big challenge. The purpose of this study was to investigate the clinical effect of valgus osteotomy in combination with dynamic hip screw...
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Article
Open AccessA group-mediated, home-based physical activity intervention for patients with peripheral artery disease: effects on social and psychological function
PAD is a disabling, chronic condition of the lower extremities that affects approximately 8 million people in the United States. The purpose of this study was to determine whether an innovative home-based walk...
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Article
Reconstruction of Kuwada grade IV chronic achilles tendon rupture by minimally invasive technique
Background: Transfer of a flexor hallucis longus (FHL) tendon can not only reconstruct the Achilles tendon but also provide ischemic tendinous tissues with a rich blood supply to enhance wound healing. This retro...
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Article
Open AccessEscin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo
Osteosarcoma is one of the most malignant neoplasms in adolescents, and it generally develops multidrug resistance. Escin, a natural mixture of triterpene saponins isolated from Aesculus hippocastanum (horse c...
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Article
Open AccessEffectiveness of transcutaneous electrical nerve stimulation for the treatment of migraine: a meta-analysis of randomized controlled trials
Migraine is now ranked as the second most disabling disorder worldwide reported by the Global Burden of Disease Study 2016. As a noninvasive neurostimulation technique, transcutaneous electrical nerve stimulat...
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Article
Imbalanced plant stoichiometry at contrasting geologic-derived phosphorus sites in subtropics: the role of microelements and plant functional group
Subtropical soils are generally characterized as deficient in phosphorus (P), calcium (Ca) and magnesium (Mg), but rich in iron (Fe) and aluminum (Al). However, soils developed in phosphate rock are extremely ...
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Article
Hydrogen Effect on the Fatigue Crack Growth in Austenitic Stainless Steel Investigated by a New Method Based on Nanohardness Distribution
A new method of nanohardness distribution for investigating the hydrogen effect on the fatigue crack in austenitic stainless steels was developed. The nanohardness distribution around the fatigue crack tip is ...
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Article
Chlorogenic acid attenuates virulence factors and pathogenicity of Pseudomonas aeruginosa by regulating quorum sensing
Quorum sensing (QS) is a cell-to-cell communication that is used by bacteria to regulate collective behaviors. Quorum sensing controls virulence factor production in many bacterial species and it is regarded a...
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Article
Open AccessAnti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma
Chimeric antigen receptor (CAR)-engineered T cells have displayed outstanding performance in the treatment of patients with hematological malignancies. However, their efficacy against solid tumors has been lar...
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Article
Open AccessCheckpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells
AZD7762 is a checkpoint kinase 1 (Chk 1) inhibitor, which has been reported to sensitize many tumor cells to DNA damage. However, whether AZD7762 could sensitize osteosarcoma cells to chemotherapy cisplatin ha...
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Article
Open AccesslncRNAs: function and mechanism in cartilage development, degeneration, and regeneration
With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and intervertebral disc degeneration (IDD), heavier financial and social burdens need to be faced. Unfortunately, there i...
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B-Cells in Cancer Immunology: For or Against Cancer Growth?
The role played by B-cells in cancer immunology is complex and somewhat controversial. Depending upon their state of activation, B-cells have had divergent roles in T-cell differentiation and effector function...
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Article
Open AccessEstrogen receptor β induces autophagy of osteosarcoma through the mTOR signaling pathway
Estrogen receptor beta (ERβ) was considered as a tumor-inhibiting factor in estrogen-sensitive malignant tumors. In this study, we intended to investigate whether ERβ was involved in inducing autophagy in oste...
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Article
Influence of Warm Predeformation Temperature on the Corrosion Property of Type 304 Austenitic Stainless Steel
The influence of predeformation temperature (100-400 °C) on the corrosion property of the predeformed 304 austenitic stainless steel (SS) in 3.5 wt.% NaCl medium was studied by electrochemical and microstructu...
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Article
Abnormal Evolution of Pitting Behavior of Warmly Pre-Strained Austenitic Stainless Steels
The effect of warm pre-strain on the corrosion behavior of 304 and 316 steels in 3.5% NaCl solution was first explored by electrochemical tests, passive film characterization, and structural analysis. The pitt...
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Article
Microstructure Evolution and Corrosion Behavior of Deformed Austenitic Stainless Steel Manufactured by Selective Laser Melting
The effect of room temperature deformation on the microstructure and corrosion behavior of selective laser-melted (SLM) 316L steel in 0.9 wt.% NaCl medium was explored by electrochemical tests, microstructural...
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Article
Plantations modified leaf elemental stoichiometry compared to the native shrub community in karst areas, Southwest of China
Nutrient limitation changed from N–P co-limitation in the native shrubs to N limitation in the plantations.