14 Result(s)
within
Huijuan Wu
Life Sciences
-
Article
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a unique component of the ubiquitin–proteasome system (UPS), which has multiple activities in maintaining intracellular ubiquitin levels. We previously repor...
-
Article
Open AccessNLRP3 associated with chronic kidney disease progression after ischemia/reperfusion-induced acute kidney injury
Nod-like receptor protein 3 (NLRP3), as an inflammatory regulator, has been implicated in acute kidney injury (AKI). Failed recovery after AKI can lead to chronic kidney disease (CKD). However, the role of NLR...
-
Article
Open AccessHippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI
Acute kidney injury (AKI) is associated with significant morbidity and its chronic inflammation contributes to subsequent chronic kidney disease (CKD) development. Yes-associated protein (YAP), the major trans...
-
Article
Effects of sulfur limitation on nitrogen and sulfur uptake and lipid accumulation in Scenedesmus acuminatus
Sulfur limitation is a frequently exploited method for inducing lipid accumulation in microalgae. However, there is little understanding of the underlying mechanism of this process. Hence, a study was conducte...
-
Article
Open AccessBone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1
Exosomes are small endogenous membrane vesicles that can mediate cell communication by transferring genetic materials. Based on that, exosomes have always been discussed as a cargo carrier for microRNA (miRNA)...
-
Article
Open AccessPulmonary alveolar regeneration in adult COVID-19 patients
-
Article
Open AccessMetformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation
Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients develo** polycystic kidney disease and leading to a decline of renal function. TSC is caused ...
-
Article
Growth, biochemical composition, and photosynthetic performance of Scenedesmus acuminatus during nitrogen starvation and resupply
Many microalgae store energy as triacylglycerols under certain environmental conditions. Nitrogen limitation is recognized as an efficient lipid-accumulation trigger in microalgae. Here, biochemical compositio...
-
Article
Open AccessInhibiting 4E-BP1 re-activation represses podocyte cell cycle re-entry and apoptosis induced by adriamycin
Podocyte loss is one of the determining factors for the progression toward glomerulosclerosis. Podocyte is terminally differentiated and does not typically proliferate following injury and loss. However, recen...
-
Article
Photosynthetic physiological performance and proteomic profiling of the oleaginous algae Scenedesmus acuminatus reveal the mechanism of lipid accumulation under low and high nitrogen supplies
In this study, we presented cellular morphological changes, time-resolved biochemical composition, photosynthetic performance and proteomic profiling to capture the photosynthetic physiological response of Scened...
-
Article
Erratum to Central European Journal of Biology, Volume 8, Issue 11
Paper by Li Li Huijuan Wu, Jialin Qian, Mingzhen Li, Yue Li, Baoming Li et al. “Decreased Na+/K+ ATPase α1 (ATP1A1) gene expression in major depression patients’ peripheral blood” in Voulme 8, Issue 11, 1077-1...
-
Article
Decreased Na+/K+ ATPase α1 (ATP1A1) gene expression in major depression patients’ peripheral blood
Major depression affects the central nervous system and thereafter the autonomic nervous system, immune system, and endocrine system. Na+/K+ ATPase, as a major mediator of cellular transmembrane ionic gradient...
-
Article
De novo next-generation sequencing, assembling and annotation of Arachis hypogaea L. Spanish botanical type whole plant transcriptome
Peanut is a major agronomic crop within the legume family and an important source of plant oil, proteins, vitamins, and minerals for human consumption, as well as animal feed, bioenergy, and health products. P...
-
Article
Natural rules for Arabidopsis thaliana pre-mRNA splicing site selection
The accurate prediction of plant pre-mRNA splicing sites has been studied extensively. The rules for plant pre-mRNA splicing still remain unknown. This study, based on confirmed sequence data, systematically a...
