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Article
Mechanism of iron on the intestinal epithelium development in suckling piglets
This study aimed to investigate the mechanism of iron on intestinal epithelium development of suckling piglets. Compared with newborn piglets, 7-day-old and 21-day-old piglets showed changes in the morphology ...
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Article
Open AccessOptimal dietary standardized ileal digestible lysine level for pigs during the grower, early and late finisher periods
Lysine (Lys) is the first limiting amino acid for pigs fed corn-soybean meal diets. Three experiments were conducted to estimate the optimal standardized ileal digestible (SID) Lys requirement for growing (Exp...
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Article
Open AccessAntioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets
In modern animal husbandry, breeders pay increasing attention to improving sow nutrition during pregnancy and lactation to favor the health of neonates. Sow milk is a main food source for piglets during their ...
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Article
Open AccessComparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells
The intestinal porcine enterocyte cell line (IPEC-J2) is a well-established model to study porcine intestinal physiology. IPEC-J2 cells undergo spontaneous differentiation during culture while changes in expre...
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Article
Effects of king grass and sugarcane top in the absence or presence of exogenous enzymes on the growth performance and rumen microbiota diversity of goats
In the present study, the feasibility of sugarcane top (ST) application in the goat’s diet was evaluated. A total of 20 goats were randomly divided into four groups. The dietary treatments were set as follows:...
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Article
Open AccessFunctional probiotics of lactic acid bacteria from Hu sheep milk
Probiotics are being considered as valuable microorganisms related to human health. Hu sheep is referred as one of the important sheep breeds in China. Goat milk produced by Hu sheep is characterized with high...
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Article
Comparison of Oral and Parenteral Iron Administration on Iron Homeostasis, Oxidative and Immune Status in Anemic Neonatal Pigs
The present study was to evaluate the consequences of iron status across oral and parenteral iron administrations in prevention of iron deficiency anemia. A total of 24 one-day-old male neonatal piglets were a...
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Article
Epidermal growth factor improves intestinal morphology by stimulating proliferation and differentiation of enterocytes and mTOR signaling pathway in weaning piglets
Epidermal growth factor (EGF) has been shown to improve piglet intestinal morphology and epithelial recovery. In an attempt to further understand the mechanisms behind these improvements, this study tested the...
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Article
Open AccessProtective effect of chicken egg yolk immunoglobulins (IgY) against enterotoxigenic Escherichia coli K88 adhesion in weaned piglets
Enterotoxigenic Escherichia coli K88 (E. coli K88) are considered as a major cause of diarrhea and death in newly weaned piglets. Oral passive immunization with chicken egg yolk immunoglobulins (IgY) have attract...
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Article
Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells
MicroRNAs play important roles in various cellular processes, including differentiation, proliferation and survival. Using a pig model, this study sought to identify the miRNAs responsible for crypt-villus axi...
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Article
Effect of dietary soy oil, glucose, and glutamine on growth performance, amino acid profile, blood profile, immunity, and antioxidant capacity in weaned piglets
Weaning stress results in gastrointestinal dysfunction and depressed performance in pigs. This study aimed to investigate the effect of soy oil, glucose, and glutamine on the growth and health of weaned piglet...
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Article
Open AccessEnergy metabolism in the intestinal crypt epithelial cells of piglets during the suckling period
We tested the hypothesis that energy metabolism in the intestinal crypt epithelial cells of piglets changes during the suckling period. The experiment began with 24 piglets from 8 litters (3 piglets per litter...
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Article
Pig models on intestinal development and therapeutics
The gastrointestinal tract plays a vital role in nutrient supply, digestion, and absorption, and has a crucial impact on the entire organism. Much attention is being paid to utilize animal models to study the ...
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Article
Open AccessEffects of weaning on intestinal crypt epithelial cells in piglets
Intestinal epithelial cells in the crypt proliferate in piglets in response to weaning. However, the underlying mechanism has been unclear. We examined 40 piglets from eight litters (five piglets per litter) t...
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Article
Open AccessEnergy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis
Intestinal epithelial cells continuously migrate and mature along crypt-villus axis (CVA), while the changes in energy metabolism during maturation are unclear in neonates. The present study was conducted to t...
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Article
Methionine restriction on lipid metabolism and its possible mechanisms
Methionine restriction (MR) exerts many beneficial effects, such as increasing longevity, decreasing oxidative damage and alleviating inflammatory responses. Much attention has been recently focused on the eff...
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Article
Ethanolamine enhances the proliferation of intestinal epithelial cells via the mTOR signaling pathway and mitochondrial function
Ethanolamine (Etn), which is the base constituent of phosphatidylethanolamine, a major phospholipid in animal cell membranes, is required for the proliferation of many types of mammalian epithelial cells. Howe...
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Article
Effects of dietary l-lysine intake on the intestinal mucosa and expression of CAT genes in weaned piglets
The objective of this study was to evaluate effects of dietary l-lysine on the intestinal mucosa and expression of cationic amino acid transporters (CAT) in weaned piglets. Twenty-eight piglets weaned at 21 days ...
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Article
Molecular cloning and expression profiling of excitatory amino acid carrier 1 in suckling Huanjiang mini-piglets with large or small body weight at birth
Dietary glutamate is extensively oxidized in enterocytes during its trans-cellular journey from the intestinal lumen to the blood. This corresponds to high energy requirement for the absorptive function and re...
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Development and Renewal of Intestinal Villi in Pigs
The gastrointestinal mucosa of pig not only acts as an organ for diet digestion and absorption but also plays an important role in fighting against pathogenic bacteria and toxic substances presented in intesti...