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Article
A Cross-Sectional Study of the Relationship Between Serum Cortisol Levels, Stress, Anxiety, and Sleep Bruxism
For better understanding the relationship between stress-related hormone and probable sleep bruxism (SB), we compared the serum level of cortisol in patients with SB and healthy individuals. Thirty-nine patien...
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Article
Open AccessSerum mir-31-5p is a reliable biomarker in patients with oral squamous cell carcinoma and oral lichen planus
MicroRNAs have been proposed as a novel regulatory biomarker for gene expression and early diagnosis of cancers. In this study, we evaluate the expression level of miR-31-5p in the serum of patients with oral ...
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Article
Relation of hepcidin gene expression in blood mononuclear cells with iron overload severity among β-thalassemia major patients
Iron overload is the main cause of morbidity and mortality in β-thalassemia major patients, and cardiac iron overload is the most common reason for death in these transfusion-dependent patients. Hepcidin, a li...
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Article
G-quadruplex forming region within WT1 promoter is selectively targeted by daunorubicin and mitoxantrone: A possible mechanism for anti-leukemic effect of drugs
Wilms tumor 1 (WT1) has long been overexpressed in acute myeloid leukemia and has a prognostic value in its diagnosis. Lately, the formation of G-quadruplexes in oncogenic promoters like WT1 has been widely inves...
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Article
JAK2 V617F Mutation in Adult T Cell Leukemia-Lymphoma
Adult T cell Leukemia/lymphoma (ATL) is a mature T-cell neoplasm that has strong association with the human T-lymphotropic virus type 1 (HTLV-I) infection. This infection is endemic in our region (north easter...
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Article
Downregulation of the WT1 gene expression via TMPyP4 stabilization of promoter G-quadruplexes in leukemia cells
The WT1 gene is an important oncogene, and its overexpression is considered as an effective target for anticancer therapy. Regulation of its gene transcription is one way for WT1-targeting drug design. Recently, ...
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Article
Absence of Helicobacter pylori infection in coronary atherosclerosis disease in Northeast of Iran
Atherosclerosis is an inflammatory disorder in which infectious agents are incriminated as contributors. It is suggested that Helicobacter pylori may be a risk factor of atherosclerosis.
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Article
Serum Immunoglobulins in Patients with Iron Deficiency Anemia
Iron deficiency is a common cause of anemia worldwide. Documentation shows that these patients have impaired immunity and are prone to infections. The aim of this study was to confirm whether serum immunoglobu...
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Article
Immunohistochemical study association between human herpesvirus 8 and multiple myeloma
Multiple myeloma (MM) is a plasma cell neoplasm characterized by a clonal proliferation of plasma cells that produce a monoclonal protein and involve the skeleton at multiple sites. Although human herpesvirus-...
