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Article
Open AccessIn silico analysis of the wild-type and mutant-type of BRCA2 gene
The aim of this study was to conduct an in silico analysis of a novel compound heterozygous variant in breast cancer susceptibility gene 2 (BRCA2) to clarify its structure–function relationship and elucidate t...
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Article
Open AccessSynergistic polarization engineering of dielectric towards low-voltage high-mobility solution-processed ultraflexible organic transistors
The emerging wearable skin-like electronics require the ultra-flexible organic transistor to operate at low voltage for electrical safety and energy efficiency and simultaneously enable high field-effect mobil...
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Article
Open AccessDNA-based molecular classifiers for the profiling of gene expression signatures
Although gene expression signatures offer tremendous potential in diseases diagnostic and prognostic, but massive gene expression signatures caused challenges for experimental detection and computational analy...
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Article
Responses of growth, yield and fruit quality of strawberry to elevated CO2, LED supplemental light, and their combination in autumn through spring greenhouse production
During the whole growth cycle growth, yield and fruit quality of strawberry are often strongly affected by insufficient CO2 and low light in greenhouse production. However, it is still not clear what extent growt...
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Article
Amyloid-β mediates intestinal dysfunction and enteric neurons loss in Alzheimer's disease transgenic mouse
Alzheimer's disease (AD) is traditionally considered as a brain disorder featured by amyloid-β (Aβ) deposition. The current study on whether pathological changes of AD extend to the enteric nervous system (ENS...
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Article
Soil organic carbon stability and exogenous nitrogen fertilizer influence the priming effect of paddy soil under long-term exposure to elevated atmospheric CO2
Soil organic carbon (SOC) stability and dynamics are greatly influenced by long-term elevated atmospheric CO2 [CO2]. The priming effect (PE) is vital in SOC stability and dynamics, but its role in paddy soil unde...
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Article
Healthy or tasty: the impact of fresh starts on food preferences
Consumers’ food decisions are at least partially determined by decision context. This research examined the role of a ubiquitous but neglected context—the time point of decision making. We explored whether and...
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Article
Open AccessReliability and validity of the Chinese version of the achievement emotions questionnaire for physical education in university students
Achievement emotions have a significant impact on both the learning process and outcomes. However, there is currently no brief and effective questionnaire available to evaluate Chinese university students' ach...
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Article
Open AccessAssociation of living environmental and occupational factors with semen quality in chinese men: a cross-sectional study
Sperm quality can be easily influenced by living environmental and occupational factors. This study aimed to discover potential semen quality related living environmental and occupational factors, expand knowl...
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Article
Open AccessPlasmonic metafibers electro-optic modulators
Digitalizing optical signals through electric driving signals, electro-optic modulators (EOMs) are one of the cardinal elements in modern optical communications. Most of current EOM devices are targeting on-ch...
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Article
An Intelligent Fault Diagnosis Method for Imbalanced Nuclear Power Plant Data Based on Generative Adversarial Networks
In the fault diagnosis problem, where sample data of fault cases are imbalanced, data generation and expansion are performed based on a generative adversarial network to obtain balanced data for training. Comb...
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Article
Open AccessCorrection: Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors
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Article
miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice
Post-stroke depression (PSD) is a serious and common complication of stroke, which seriously affects the rehabilitation of stroke patients. To date, the pathogenesis of PSD is unclear and effective treatments ...
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Article
Open AccessTM9SF4 is an F-actin disassembly factor that promotes tumor progression and metastasis
F-actin dynamics is crucial for many fundamental properties of cancer cells, from cell-substrate adhesion to migration, invasion and metastasis. However, the regulatory mechanisms of actin dynamics are still i...
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Article
Open AccessRoles of lncRNA LVBU in regulating urea cycle/polyamine synthesis axis to promote colorectal carcinoma progression
Altered expression of Urea Cycle (UC) enzymes occurs in many tumors, resulting a metabolic hallmark termed as UC dysregulation. Polyamines are synthesized from ornithine, and polyamine synthetic genes are elev...
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Article
Phytoremediation of cadmium-contaminated soils by Solanum nigrum L. enhanced with biodegradable chelating agents
The application of biodegradable chelating agents to enhance phytoremediation is a low-cost and promising method to improve the remediation efficiency of heavy metal–contaminated soil. The effects of N, N-bis ...
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Article
VGLUT3 neurons in median raphe control the efficacy of spatial memory retrieval via ETV4 regulation of VGLUT3 transcription
The raphe nucleus is critical for feeding, rewarding and memory. However, how the heterogenous raphe neurons are molecularly and structurally organized to engage their divergent functions remains unknown. Here...
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Article
Integrated transcriptomic and metabolomic analyses of Caucasian clover (Trifolium ambiguum Bieb.) in response to freezing stress
Caucasian clover (Trifolium ambiguum Bieb.) is a perennial leguminous herbage with unique properties, such as resistance to cold, drought, and grazing. However, the response of Caucasian clover to freezing stress...
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Article
Open AccessVariable universe adaptive fuzzy sliding mode projective synchronization of hyperjerk system based on disturbance observer
In this paper, a sliding mode projective synchronization strategy based on disturbance observer and fuzzy system is presented to implement projective synchronization of hyperjerk system with low time-varying d...
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Article
Microbial dysbiosis together with nutrient imbalance cause the replant problem of upper six flue-cured tobacco in Central Henan
Replant problem in agriculture is popular and has restricted the development of tobacco industry. To identify the key soil factors affecting replant problem of tobacco, rhizosphere soils and flue-cured tobacco...
