5 Result(s)
within
HongLian Li
English
Cell Biology
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Article
Open AccessA novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies
Intraneuronal accumulation of hyperphosphorylated tau is a hallmark pathology shown in over twenty neurodegenerative disorders, collectively termed as tauopathies, including the most common Alzheimer’s disease...
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Article
Open AccessThe bZIP transcription factor FpAda1 is essential for fungal growth and conidiation in Fusarium pseudograminearum
Fusarium pseudograminearum is an important pathogen of Fusarium crown rot and Fusarium head blight, which is able to infect wheat and barley worldwide, causing great economic losses. Transcription factors (TFs) o...
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Article
Expression of Fusarium pseudograminearum FpNPS9 in wheat plant and its function in pathogenicity
Fusarium pseudograminearum-induced crown rot causes significant reduction to wheat production worldwide. To date, efforts to develop effective resistance to this disease have been hampered by the quantitative nat...
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Article
Purα Repaired Expanded Hexanucleotide GGGGCC Repeat Noncoding RNA-Caused Neuronal Toxicity in Neuro-2a Cells
Expanded hexanucleotide GGGGCC repeat in a noncoding region of C9ORF72 is the most common cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). However, its molecular pathogenesis rem...
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Article
Neuroprotective Effects of Kinetin Against Glutamate-Induced Oxidative Cytotoxicity in HT22 Cells: Involvement of Nrf2 and Heme Oxygenase-1
Oxidative stress is considered as one of key factors related to Alzheimer’s disease (AD), while kinetin (KT) has been reported to exert anti-oxidative activities as well as neuroprotective effects both in vivo...
