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Open AccessGene delivery to breast cancer by incorporated EpCAM targeted DARPins into AAV2
The aim of this study is to evaluate an AAV vector that can selectively target breast cancer cells and to investigate its specificity and anti-tumor effects on breast cancer cells both in vitro and in vivo, of...
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Article
Study on the Relationship Between Differentially Expressed Proteins in Breast Cancer and Lymph Node Metastasis
Lymph node metastasis is a cause of poor prognosis in breast cancer. Mass spectrometry-based proteomics aims to map the protein landscapes of biological samples and profile tumors more comprehensively. Here, p...
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Article
On hot deformation behavior and workability characteristic of 42CrMo4 steel based on microstructure and processing map
In order to determine the safe region of 42CrMo4 steel during hot working and obtain excellent workability, the hot deformation behavior at the temperatures of 850–1150 °C and the strain rates of 0.01–10 s−1 was ...
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Article
Effect of Cooling Rate and Coiling Temperature on Microstructure and Precipitation Behavior of a 700 MPa Weathering Steel
The microstructures, mechanical properties and precipitation behavior of a high-Ti low-C weathering steel obtained by thermo-mechanical controlled process were investigated by means of electron backscatter dif...
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Article
Inhibitory effects of 3-(methylthio) propyl isothiocyanate in comparison with benzyl isothiocyanate on Listeria monocytogenes
The objective of the current study was to investigate the inhibitory effects of benzyl isothiocyanate (BITC) and 3-(methylthio) propyl isothiocyanate (MTPITC) on Listeria monocytogenes (L. monocytogenes). The com...
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Exploration of the antimicrobial activity of benzyl isothiocyanate against Salmonella enterica serovar Typhimurium
Mounting evidence suggests that benzyl isothiocyanate (BITC), derived from cruciferous vegetables, could be an effective antimicrobial compound against a wide range of food-borne bacteria. This research invest...
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Article
Open AccessOptimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer’s Disease Rat Model
Angelica (A.) sinensis is used as a traditional medical herb for the treatment of neurodegeneration, aging, and inflammation in Asia. A. sinensis optimal formula (AOF) is the best combination in A. sinensis that ...
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Article
Open AccessDo Rural Residents in China Understand EQ-5D-5L as Intended? Evidence From a Qualitative Study
The 5-level EQ-5D (EQ-5D-5L) has been increasingly used in China to measure the health status of the general population and patients. However, its content validity among rural residents in China has not been f...
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Article
The Relationship Between White Adipose Tissue Inflammation and Overweight/Obesity in Chinese Female Breast Cancer: A Retrospective Study
This study aims to investigate the relationship between breast white adipose tissue (WAT) inflammation and being overweight or obese, menopausal status, and metabolic syndrome-related indicators in breast canc...
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Article
Cognition and Sociodemographic Determinants for Effective Pain Control in Patients with Cancer Pain: a Cross-sectional Survey in China
This cross-sectional study aimed to investigate cancer patients’ cognitive level of pain control and to evaluate the patient-related factors or barriers to effective cancer pain management in China. In seven t...
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Article
Significance of Finish Cooling Temperature to Microstructure and Property Relationship of Low-Carbon V-N-Cr Microalloyed High-Strength Steel
Herein, three final cooling temperatures were employed to achieve high strength and toughness communication in the V-N-Cr microalloyed steels. This study shows that V-N-Cr microalloyed steel primarily consiste...
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Article
Effects of O3 stress on physico-chemical and biochemical properties and composition of main microbial groups of a soil cropped to soybean
Tropospheric O3 (ozone) stress can negatively affect forest productivity and crop yields. Yet, relatively little attention has been paid to the effects of O3 stress on belowground system. Here, a pot experiment w...
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Article
MYC protein expression is associated with poor prognosis in diffuse large B cell lymphoma patients treated with RCHOP chemotherapy
This study aims to investigate the prognostic significance of the MYC protein expression in diffuse large B cell lymphoma (DLBCL) patients treated with RCHOP (rituximab plus cyclophosphamide, doxorubicin, vinc...
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Article
Parameters of the secondary electron yield from metal
Based on a simple classical model that primary electrons interact with the electron of a lattice via a Coulomb force, the condition that the lattice scattering can be ignored and the energy band of metal, we d...
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Article
Lanthanide–Bismuth Heterometallics Combined Lanthanide Metal Complexes with Bismuth Iodides: Structures and Properties
Two new lanthanide–bismuth heterometallic hybrids, [Dy(DMF)8](Bi2I9) (1) and [Er(DMF)8](Bi2I9) (2) (N,N’-dimethylformamide (DMF)) have been synthesised by solution processes, which assume significance for their f...
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Article
Open AccessPrevalence of the metabolic syndrome in Pudong New Area of Shanghai using three proposed definitions among Chinese adults
The prevalence of metabolic syndrome (MS) has been increasing in China in recent years. The aim of this study is to estimate and compare the prevalence of MS among Chinese adults in Shanghai, one of the most e...
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Article
Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with β-catenin
Lgr5 is a member of the G protein receptor super-family and was shown recently to be a stem cell marker for cells with intestinal differentiation. Its over-expression has been demonstrated in hepatocellular, b...
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Article
The synthesis and crystal structures of new 2-aminomethylbenzimidazole Zinc(II) complexes exhibiting luminescence
Two new blue luminescent Zn(II) complexes, [ZnL2(H2O)]Cl2 · H2O (1) and [ZnL2Cl][ZnLCl2] · NO3 (2) (L = 2-aminomethylbenzimidazole) have been synthesized and characterized spectroscopically and crystallographical...