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Article
Open AccessMCAs in Arabidopsis are Ca2+-permeable mechanosensitive channels inherently sensitive to membrane tension
Mechanosensitive (MS) ion channels respond to mechanical stress and convert it into intracellular electric and ionic signals. Five MS channel families have been identified in plants, including the Mid1-Complem...
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Article
The root growth reduction in response to mechanical stress involves ethylene-mediated microtubule reorganization and transmembrane receptor-mediated signal transduction in Arabidopsis
We found that mutations in a Ca 2+ -permeable mechanosensitive channel MCA1, an ethylene-regulated microtubule-associ...
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Article
Open AccessThe gravistimulation-induced very slow Ca2+ increase in Arabidopsis seedlings requires MCA1, a Ca2+-permeable mechanosensitive channel
Gravity is a critical environmental factor affecting the morphology and function of plants on Earth. Gravistimulation triggered by changes in the gravity vector induces an increase in the cytoplasmic free calc...
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Article
Open AccessCa2+-permeable mechanosensitive channels MCA1 and MCA2 mediate cold-induced cytosolic Ca2+ increase and cold tolerance in Arabidopsis
Cold shock triggers an immediate rise in the cytosolic free calcium concentration ([Ca2+]cyt) in Arabidopsis thaliana and this cold-induced elevation of [Ca2+]cyt is inhibited by lanthanum or EGTA. It is suggeste...
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Molecular Mechanisms of Mechanosensing and Mechanotransduction
Mechanical stimuli, such as touch, bending, gravity, and wounding, influence plant growth and development through the activation of intracellular signaling pathways and gene expression. Therefore, mechanosensi...
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Article
Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response
A key molecule of sensing machineries essential for survival upon hypo-osmotic shock is the mechanosensitive channel. The bacterial mechanosensitive channel MscS functions directly for this purpose by releasin...
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Article
Involvement of the putative Ca2+-permeable mechanosensitive channels, NtMCA1 and NtMCA2, in Ca2+ uptake, Ca2+-dependent cell proliferation and mechanical stress-induced gene expression in tobacco (Nicotiana tabacum) BY-2 cells
To gain insight into the cellular functions of the mid1-complementing activity (MCA) family proteins, encoding putative Ca2+-permeable mechanosensitive channels, we isolated two MCA homologs of tobacco (Nicotiana...
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Article
Open AccessPlasma membrane protein OsMCA1 is involved in regulation of hypo-osmotic shock-induced Ca2+influx and modulates generation of reactive oxygen species in cultured rice cells
Mechanosensing and its downstream responses are speculated to involve sensory complexes containing Ca2+-permeable mechanosensitive channels. On recognizing osmotic signals, plant cells initiate activation of a wi...
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Article
Mechanoreception in motile flagella of Chlamydomonas
On collision, cilia and flagella swim backwards owing to the generation of mechanoreceptor potential. Transient Receptor Potential 11 is found to localize to the proximal region of Chamydomonas flagella and to me...
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Article
Roles of Ca2+ in hyphal and yeast-form growth inCandida albicans. Growth regulation by altered extracellular and intracellular free Ca2+ concentrations
The dimorphic fungusCandida albicans has both a yeast form and a hyphal form. When yeast-form cells were starved and then transferred to aN-acetylglucosamine medium, the formation of true hyphae from the unbudded...
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Article
Calmodulin-dependent protein kinase II and calmodulin are required for induced thermotolerance in Saccharomyces cerevisiae
We show here that yeast mutants lacking calmodulin-dependent protein kinase II fail to fully acquire induced thermotolerance. A similar result was also obtained with mutants depending solely on either the N-te...
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Article
Yeast heat-shock protein of Mr 48,000 is an isoprotein of enolase
Exposure of cells or tissues of various living organisms to elevated temperatures induces the synthesis of a family of specific proteins called heat-shock proteins (HSPs)1–3. This phenomenon has so far been inves...
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Article
Regulation of polar surface structures in Caulobacter crescentus: Pleiotropic mutations affect the coordinate morphogenesis of flagella, pili and phage receptors
A large number of Caulobacter mutants resistant to DNA or RNA phages were isolated. These phage-resistant mutants exhibited phenotypic variations with respect to cell motility and sensitivity to other phages.
