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Article
Variations in Autoregulation-Based Optimal Cerebral Perfusion Pressure Determination Using Two Integrated Neuromonitoring Platforms in a Trauma Patient
Neuromonitoring devices are often used in traumatic brain injury. The objective of this report is to raise awareness concerning variations in optimal cerebral perfusion pressure (CPPopt) determination using ex...
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Article
Open AccessSex-related differences in adult patients with status epilepticus: a seven-year two-center observation
Conflicting findings exist regarding the influence of sex on the development, treatment, course, and outcome of status epilepticus (SE). Our study aimed to investigate sex-related disparities in adult SE patie...
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Article
Open AccessNonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged
Seizures and status epilepticus (SE) are detected in almost a third of the comatose cardiac arrest survivors. As the literature is quite exhaustive regarding SE with motor symptoms in those patients, little is...
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Article
Open AccessThe Antiedematous Effect of Exogenous Lactate Therapy in Traumatic Brain Injury: A Physiological and Mechanistic Approach
Sodium lactate (SL) has been described as an efficient therapy in treating raised intracranial pressure (ICP). However, the precise mechanism by which SL reduces intracranial hypertension is not well defined. ...
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Article
Open AccessManagement and prevention of anemia (acute bleeding excluded) in adult critical care patients
Anemia is very common in critical care patients, on admission (affecting about two-thirds of patients), but also during and after their stay, due to repeated blood loss, the effects of inflammation on erythrop...
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Article
Open AccessTime course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study
Fluid challenge (FC) is one of the most common practices in Intensive Care Unit (ICU). The present study aimed to evaluate whether echocardiographic assessment of the response to FC at the end of the infusion ...
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Article
Open AccessExperts’ guidelines of intubation and extubation of the ICU patient of French Society of Anaesthesia and Intensive Care Medicine (SFAR) and French-speaking Intensive Care Society (SRLF)
Intubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required i...
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Article
Open AccessRisk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures
Patients liberated from invasive mechanical ventilation are at risk of extubation failure, including inability to breathe without a tracheal tube (airway failure) or without mechanical ventilation (non-airway ...
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Article
Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations
To report the ESICM consensus and clinical practice recommendations on fluid therapy in neurointensive care patients.
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Article
Open AccessTracheotomy in the intensive care unit: guidelines from a French expert panel
Tracheotomy is widely used in intensive care units, albeit with great disparities between medical teams in terms of frequency and modality. Indications and techniques are, however, associated with variable lev...
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Chapter
Energy Metabolism: From the Organ to the Cell
Our survival state depends on serial metabolic reactions needing energy. Our environmental feed is the principal source of this energy. The purpose of this chapter is to describe all the organic and cellular m...
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Chapter
Acidosis: Diagnosis and Treatment
Acidosis is characterized by a decrease in plasma pH. The first chapter will focus on the pathophysiological principles responsible for the development of an acidosis. Clinical signs of an acidosis are not spe...
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Chapter
Interpretation of Acid-Base Disorders
The definition of an acid or a base varies largely according to the context. From a physiological point of view, an acid or an alkaline solution is characterized by its capacity to release or conversely to con...
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Article
ICU specialists facing terrorist attack: the Nice experience
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Article
Open AccessSeawater drowning-associated pneumonia: a 10-year descriptive cohort in intensive care unit
Pneumonia is one of the major complications of drowning, but the optimal empirical antibiotic treatment is not clearly defined. Multidrug-resistant (MDR) bacteria and fungi have been identified in a recent se...
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Article
Open AccessProceedings of Réanimation 2017, the French Intensive Care Society International Congress
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Article
Open AccessEarly and persistent high level of PS 100β is associated with increased poor neurological outcome in patients with SAH: is there a PS 100β threshold for SAH prognosis?
Protein S100β (PS100 β) and neuron specific enolase (NSE) have been described as biological markers of neuronal damage. The purpose of our study was to assess the prognosis thresholds of these biomarkers in su...
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Chapter
The Stress Response after Traumatic Brain Injury: Metabolic and Hormonal Aspects
The pathophysiology of TBI can be considered as a dual insult composed of primary and secondary injuries. Growing experimental and clinical evidence suggests that disturbances of cerebral energy metabolism are...
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Article
Point-of-care ultrasound in intensive care units: assessment of 1073 procedures in a multicentric, prospective, observational study
To describe current use and diagnostic and therapeutic impacts of point-of-care ultrasound (POCUS) in the intensive care unit (ICU).
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Article
Normobaric Hyperoxia is Associated with Increased Cerebral Excitotoxicity After Severe Traumatic Brain Injury
Normobaric oxygen therapy is frequently applied in neurocritical care, however, whether supplemental FiO2 has beneficial cerebral effects is still controversial. We examined in patients with severe traumatic bra...
