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  1. Article

    Open Access

    Predicting frailty in older adults using vocal biomarkers: a cross-sectional study

    Frailty is a common issue in the aging population. Given that frailty syndrome is little discussed in the literature on the aging voice, the current study aims to examine the relationship between frailty and v...

    Yu-Chun Lin, Huang-Ting Yan, Chih-Hsueh Lin, Hen-Hong Chang in BMC Geriatrics (2022)

  2. Article

    Open Access

    Identifying the functions and biomarkers of Codonopsis pilosula and Astragalus membranaceus aqueous extracts in hepatic cells

    Homeostasis is a crucial concept used to describe the condition of patients and the roles of herbs in traditional Chinese medicine. Qi-deficiency pattern is one of the conditions when loss of homeostasis and i...

    Pin-Hao Ko, Chiung-Wei Huang, Hen-Hong Chang, Eric Y. Chuang in Chinese Medicine (2019)

  3. Article

    Open Access

    Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

    It is known that the medicinal herb Alpinia oxyphylla Miq. is widely used as a remedy for diarrhea as well as the symptoms accompanying hypertension and cerebrovascular disorders. Moreover, it has also been re...

    Yung-Ming Chang, Hen-Hong Chang in BMC Complementary and Alternative Medicine (2017)

  4. Article

    Open Access

    Transformation of 5-D itch scale and numerical rating scale in chronic hemodialysis patients

    Pruritus is a common and frustrating symptom in hemodialysis (HD) patients and 5-D itch scale is proposed as a reliable measurement of pruritus. However, information regarding 5-D itch scale categories is curr...

    Jia-Wen Lai, Hung-Chih Chen, Che-Yi Chou, Hung-Rong Yen, Tsai-Chung Li in BMC Nephrology (2017)

  5. Article

    Open Access

    Treatment of allergic rhinitis with acupoint herbal plaster: an oligonucleotide chip analysis

    Allergic rhinitis is regarded as an imbalanced Th1/Th2 cell-mediated response. The present study used microarray analysis to compare gene expression levels between allergic rhinitis patients before and after a...

    Horng-Sheng Shiue, Yun-Shien Lee in BMC Complementary and Alternative Medicine (2016)

  6. Article

    Open Access

    Validation of a new simple scale to measure symptoms in heart failure from traditional Chinese medicine view: a cross-sectional questionnaire study

    Current clinical practices used to functionally classify heart failure (HF) are time-consuming, expensive, or require complex calculations. This study aimed to design an inquiry list from the perspective of tr...

    Tieh-Cheng Fu, Yi-Chung Lin, Ching-Mao Chang in BMC Complementary and Alternative Medicine (2016)

  7. Article

    Open Access

    The association between arterial stiffness and tongue manifestations of blood stasis in patients with type 2 diabetes

    Diabetes mellitus (DM) is a hypercoagulable state and is associated with highly increased risk of vascular complications. In the theory of traditional Chinese medicine (TCM), these vascular complications are c...

    Po-Chi Hsu, Yu-Chuen Huang, John Y. Chiang in BMC Complementary and Alternative Medicine (2016)