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    Article

    J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy

    Hepatic encephalopathy (HE) is a common neurological manifestation of liver cirrhosis and is characterized by an increase of ammonia in the brain accompanied by a disrupted neurotransmitter balance, including ...

    Helge Jörn Zöllner, Thomas A. Thiel, Nur-Deniz Füllenbach in Metabolic Brain Disease (2023)

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    Article

    Covert hepatic encephalopathy: elevated total glutathione and absence of brain water content changes

    Recent pathophysiological models suggest that oxidative stress and hyperammonemia lead to a mild brain oedema in hepatic encephalopathy (HE). Glutathione (GSx) is a major cellular antioxidant and known to be i...

    Georg Oeltzschner, Markus Butz, Frithjof Wickrath in Metabolic Brain Disease (2016)

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    Article

    Low visual cortex GABA levels in hepatic encephalopathy: links to blood ammonia, critical flicker frequency, and brain osmolytes

    The pathogenesis of hepatic encephalopathy (HE) is not fully understood yet. Hyperammonemia due to liver failure and subsequent disturbance of cerebral osmolytic balance is thought to play a pivotal role in th...

    Georg Oeltzschner, Markus Butz, Thomas J. Baumgarten in Metabolic Brain Disease (2015)

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    Article

    Lesion patterns in successful and failed thrombolysis in middle cerebral artery stroke

    Thrombolysis has been shown to improve neurological recovery in acute stroke. But the response to thrombolysis is variable across patients. We sought to investigate this variability by analyzing the lesion pat...

    Rüdiger J. Seitz, Verena Sondermann, Hans-Jörg Wittsack, Mario Siebler in Neuroradiology (2009)

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    Open Access

    On the neural networks of empathy: A principal component analysis of an fMRI study

    Human emotional expressions serve an important communicatory role allowing the rapid transmission of valence information among individuals. We aimed at exploring the neural networks mediating the recognition o...

    Jason S Nomi, Dag Scherfeld, Skara Friederichs in Behavioral and Brain Functions (2008)