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The Marsupial Major Histocompatibility Complex

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  1. Article

    Open Access

    Exploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities

    Bovine babesiosis, caused by different Babesia spp. such as B. bovis, B. bigemina, B. divergens, and B. major, is a global disease that poses a serious threat to livestock production. Babesia bovis infections are...

    John Harvey M. Santos, Hannah V. Siddle, Ali Raza in Parasites & Vectors (2023)

  2. Article

    Open Access

    The role of MHC genes in contagious cancer: the story of Tasmanian devils

    The Tasmanian devil, a marsupial species endemic to the island of Tasmania, harbours two contagious cancers, Devil Facial Tumour 1 (DFT1) and Devil Facial Tumour 2 (DFT2). These cancers pass between individual...

    Alison Caldwell, Hannah V. Siddle in Immunogenetics (2017)

  3. Article

    Erratum to: Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development

    Marilyn B Renfree, Anthony T Papenfuss, Janine E Deakin, James Lindsay in Genome Biology (2011)

  4. Article

    Open Access

    The tammar wallaby major histocompatibility complex shows evidence of past genomic instability

    The major histocompatibility complex (MHC) is a group of genes with a variety of roles in the innate and adaptive immune responses. MHC genes form a genetically linked cluster in eutherian mammals, an organiza...

    Hannah V Siddle, Janine E Deakin, Penny Coggill, Laurens G Wilming in BMC Genomics (2011)

  5. Article

    Open Access

    Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development

    We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hop** mammals that symbolize Australia to be sequenced...

    Marilyn B Renfree, Anthony T Papenfuss, Janine E Deakin, James Lindsay in Genome Biology (2011)

  6. Article

    Open Access

    MHC-linked and un-linked class I genes in the wallaby

    MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions. However, there is a f...

    Hannah V Siddle, Janine E Deakin, Penny Coggill, Elizabeth Hart in BMC Genomics (2009)

  7. Article

    The Immune Response of the Tasmanian Devil (Sarcophilus harrisii) and Devil Facial Tumour Disease

    One of the most remarkable aspects of Devil Facial Tumour Disease (DFTD) is its infectious nature, and for successful transmission it must avoid detection by the devil’s immune system. For this to occur, the d...

    Gregory M. Woods, Alexandre Kreiss, Katherine Belov, Hannah V. Siddle in EcoHealth (2007)