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Open AccessElevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness
Ductal carcinoma in situ (DCIS) is the most common type of in situ premalignant breast cancers. What drives DCIS to invasive breast cancer is unclear. Basal-like invasive breast cancers are aggressive. We have...
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Breast Cancer Invasion and Metastasis
Breast cancer is the most common malignancy among western women, and 10–15 % of all breast cancer patients develop and ultimately succumb to metastatic disease. In breast cancer, malignant cells disseminate th...