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Article
The Effect of Crosslinking Density on Nasal Chondrocytes’ Redifferentiation
Hydrogels appear to be an attractive class of biomaterial for cartilage tissue engineering due to their high water content, excellent biocompatibility, tunable stiffness, etc. The crosslinking density of the h...
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Article
Algorithmically designed flaps in tongue reconstruction: a feasibility analysis
Despite the significance and complexity of tongue reconstruction surgery, a digital tool for flap design is currently lacking. This study investigates the effectiveness of employing inverse finite element meth...
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Article
Open AccessAdvanced mandibular reconstruction with fibular free flap and alloplastic TMJ prosthesis with digital planning
Resection of the mandible and temporomandibular joint (TMJ) without formal reconstruction is a devastating condition that negatively affects all aspects of the patient’s life. We have approached the reconstruc...
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Article
Feasibility and safety of Heavy Lifting Strength Training in Head and Neck Cancer survivors post-surgical neck dissection (the LIFTING trial)
Light-to-moderate intensity strength training (LMST) improves muscular strength, physical functioning, and some side effects in head and neck cancer survivors (HNCS). Heavy lifting strength training (HLST) may...
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Article
Open AccessThe effect of insurance status on treatment modality in advanced oral cavity cancer
Insurance status has been shown to impact survival outcomes. We sought to determine whether insurance affects the choice of treatment modality among patients with advanced (T4) oral cavity squamous cell carcin...
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Article
Open AccessSystematic review of validated parent-reported questionnaires assessing swallowing dysfunction in otherwise healthy infants and toddlers
There has been increasing interest in the management of oropharyngeal swallowing dysfunction (SwD). Its prevalence, particularly in otherwise healthy infants and toddlers (OHITs), is underappreciated. As the s...
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Article
Open AccessUtility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules
Mutations involving BRAF and TERT are important predictors of disease severity in thyroid cancer, but molecular testing is limited by cost and lack of adequate tissue sample. This study aimed to assess the uti...
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Article
Open AccessRecommendations from the Canadian Association of Head and Neck Surgical Oncology for the Management of Head and Neck Cancers during the COVID-19 pandemic
The SARS-CoV-2 virus (COVID19) pandemic has placed extreme pressures on the Canadian Healthcare system. Many health care regions in Canada have cancelled or limited surgical and non-surgical interventions on p...
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Article
Open AccessTelephone consultations with otolaryngology – head and neck surgery reduced emergency visits and specialty consultations in northern Alberta
RAAPID (Referral, Access, Advice, Placement, Information, and Destination) is a 24-h call center in Alberta, Canada, facilitating urgent telephone consultations between physicians and specialists. We evaluated...
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Article
Open AccessThe effect of second hand smoke in patients with squamous cell carcinoma of the head and neck
Active tobacco smoking is a well-known risk factor for head and neck malignancy, and strong evidence has associated tobacco as the main carcinogenic factor in squamous cell cancers of this region. Evidence sup...
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Article
Open AccessDonor site morbidity following radial forearm free flap reconstruction with split thickness skin grafts using negative pressure wound therapy
Donor site complications secondary to radial forearm free flap (RFFF) reconstruction can limit recovery. Optimizing hand and wrist function in the post-operative period may allow more efficient self-care and r...
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Article
Open AccessEGFR as a biomarker of smoking status and survival in oropharyngeal squamous cell carcinoma
This study aims to investigate EGFR as a prognostic biomarker in oropharyngeal squamous cell carcinoma (OPSCC).
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Article
Open AccessValidation of a novel method for localization of parathyroid adenomas using SPECT/CT
Accurate localization of parathyroid adenomas is of critical importance in surgical planning for minimally invasive parathyroidectomy. SPECT/CT is considered the investigation of choice but has limitations reg...
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Article
Open AccessAnalytic and clinical validity of thyroid nodule mutational profiling using droplet digital polymerase chain reaction
Recent guidelines for the management of thyroid nodules incorporate mutation testing as an adjunct for surgical decision-making, however current tests are costly with limited accuracy. Droplet digital PCR (ddP...
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Article
Open AccessThe impact of human papillomavirus (HPV) status on functional outcomes and quality of life (QOL) after surgical treatment of oropharyngeal carcinoma with free-flap reconstruction
To determine the impact of Human Papillomavirus (HPV) status on speech, swallowing, and quality of life (QOL) outcomes after surgical treatment of oropharyngeal cancer (OPSCC).
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Article
Open AccessMulti-dimensional analysis of oral cavity and oropharyngeal defects following cancer extirpation surgery, a cadaveric study
Defects following resection of tumors in the head and neck region are complex; more detailed and defect-specific reconstruction would likely result in better functional and cosmetic outcomes. The objectives of...
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Article
Open AccessBrief electrical stimulation and synkinesis after facial nerve crush injury: a randomized prospective animal study
Recent studies have examined the effects of brief electrical stimulation (BES) on nerve regeneration, with some suggesting that BES accelerates facial nerve recovery. However, the facial nerve outcome measurem...
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Article
Open AccessIntraoperative Brief Electrical Stimulation of the Spinal Accessory Nerve (BEST SPIN) for prevention of shoulder dysfunction after oncologic neck dissection: a double-blinded, randomized controlled trial
Shoulder dysfunction is common after neck dissection for head and neck cancer (HNC). Brief electrical stimulation (BES) is a novel technique that has been shown to enhance neuronal regeneration after nerve inj...
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Article
Open AccessPractices regarding human Papillomavirus counseling and vaccination in head and neck cancer: a Canadian physician questionnaire
Human papillomavirus (HPV) has recently been implicated as a causative agent in a rapidly growing number of oropharyngeal cancers. Emerging literature supports the hypothesis that HPV vaccination may protect a...
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Article
Open AccessCorrection to: Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network