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    Article

    CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson’s Disease

    Genetic studies of familial forms of Parkinson’s disease (PD) have shown that the ZNF543 gene is a candidate gene that operates relevant to this disease. However, until now, there is no evidence for ZNF543 gene f...

    Mohammad Hashemabadi, Hosseinali Sasan, Mojdeh Amandadi in Molecular Biotechnology (2023)

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    Article

    An intelligent DNA nanorobot for detection of MiRNAs cancer biomarkers using molecular programming to fabricate a logic-responsive hybrid nanostructure

    Herein, we designed a DNA framework-based intelligent nanorobot using toehold-mediated strand displacement reaction-based molecular programming and logic gate operation for the selective and synchronous detect...

    Amin Mirzaiebadizi, Hadi Ravan, Shahriar Dabiri in Bioprocess and Biosystems Engineering (2022)

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    Colorimetric nanoplatform for visual determination of cancer cells via target-catalyzed hairpin assembly actuated aggregation of gold nanoparticles

    According to aptamer-mediated hairpin DNA cascade amplifier and gold nanoparticles aggregation, an optical platform for cancer cells determination has been proposed. High-affinity chimeric aptamers were used f...

    Hadi Ravan, Akram Norouzi, Nima Sanadgol, Elyas Hosseinzadeh in Microchimica Acta (2020)

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    DNAzyme-embedded hyperbranched DNA dendrimers as signal amplifiers for colorimetric determination of nucleic acids

    A DNAzyme-embedded hyperbranched DNA dendrimer is used as a colorimetric signal amplifier in an ultrasensitive detection scheme for nucleic acids. The hyperbranched DNA dendrimers were constructed by single-st...

    Hadi Ravan, Tahereh Fozooni, Mojdeh Amandadi, Hosseinali Sasan in Microchimica Acta (2018)

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    Study the Microbial Communities’ Changes in Desert and Farmland Soil After Crude Oil Pollution

    Soil pollution by petroleum hydrocarbons is a widespread problem which has disturbing effects on the composition and diversity of microbial communities. The aim of this research is study the response of soil m...

    Nasrin Ansari, Mehdi Hassanshahian in International Journal of Environmental Res… (2018)

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    Signal Amplification Technologies for the Detection of Nucleic Acids: from Cell-Free Analysis to Live-Cell Imaging

    Due to their unique properties, such as programmability, ligand-binding capability, and flexibility, nucleic acids can serve as analytes and/or recognition elements for biosensing. To improve the sensitivity o...

    Tahereh Fozooni, Hadi Ravan, Hosseinali Sasan in Applied Biochemistry and Biotechnology (2017)

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    Article

    Analysis of yeh Fimbrial Gene Cluster in Escherichia coli O157:H7 in Order to Find a Genetic Marker for this Serotype

    yeh fimbrial gene cluster encodes a type of putative fimbrial complex belonging to chaperone–usher assembly pathway. Recent studies have shown that yeh fimbrial gene cluster is present in 94 % of...

    Hadi Ravan, Mojdeh Amandadi in Current Microbiology (2015)

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    Development of a new loop-mediated isothermal amplification assay for prt (rfbS) gene to improve the identification of Salmonella serogroup D

    Loop-mediated isothermal amplification (LAMP) is a promising nucleic acid assay for rapid and cost-effective detection of pathogen-specific sequences within a sample. Development of an appropriate taxonomic gr...

    Hadi Ravan, Razieh Yazdanparast in World Journal of Microbiology and Biotechnology (2012)