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  1. Article

    Open Access

    Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder

    The SLC1A1 gene, which encodes the neuronal glutamate transporter, EAAC1, has consistently been implicated in obsessive-compulsive disorder (OCD) in genetic studies. Moreover, neuroimaging, biochemical and clinic...

    B Porton, B D Greenberg, K Askland, L M Serra, J Gesmonde… in Translational Psychiatry (2013)

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    Reference Work Entry In depth

    Synaptic Vesicle Associated Proteins and Schizophrenia

    There is increasing evidence implicating proteins associated with the synaptic vesicle, a presynaptic organelle that is essential for neurotransmission and synaptic connectivity, to schizophrenia. This chapter...

    H. T. Kao, B. Porton in Handbook of Neurochemistry and Molecular Neurobiology (2009)

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    Article

    Rapid telomere erosion in schizophrenia

    H-T Kao, R M Cawthon, L E DeLisi, H C Bertisch, F Ji, D Gordon… in Molecular Psychiatry (2008)

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    Chapter and Conference Paper

    Serotonin Receptor Subtypes

    The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless gen...

    P. R. Hartig, N. Adham, J. Zgombick, M. Macchi… in Clinical Pharmacology in Psychiatry (1993)

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    Chapter

    Molecular biology of 5-HT, receptors

    Five human serotonin receptor subtypes belonging to the 5-HT, subfamily (5-HT,A, 5 HT,Dœ, 5-HT,Dß [and its species homologue: rat 5-HT,], 5- HT„, and 5-HT„) have now been cloned and characterized. The cloning of ...

    P. Hartig, N. Adham, J. Bard, A. Hou-yu, H.-T. Kao, M. Macchi, L. Schechter… in Serotonin (1993)

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    Chapter

    Molecular Diversity of HLA-DRw6 Haplotypes

    Two subdivisions of the HLA-DRw6 haplotype have recently been defined serologically as DRw13 and DRw14. We sought to investigate the molecular basis for this serological difference by sequencing the DRß 1 chai...

    T. C. Takahashi, H. T. Kao, J. C. Tang, P. Gregersen, J. Silver… in Immunobiology of HLA (1989)

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    Chapter

    Detection of an Adenovirus E1A-like Activity in Mammalian Cells

    The E1A gene product of adenovirus is responsible for the activation of early viral transcription during a lytic infection (Jones & Shenk, 1979; Berk et al., 1979; Nevins, 1981). We have previously proposed th...

    J. R. Nevins, M. J. Imperiale, H.-T. Kao, S. Strickland… in Oncogenes in B-Cell Neoplasia (1984)