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Article
Biological responses of midge (Chironomus riparius) and lamprey (Lampetra fluviatilis) larvae in ecotoxicity assessment of PCDD/F-, PCB- and Hg-contaminated river sediments
We evaluated the utility of chironomid and lamprey larval responses in ecotoxicity assessment of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/F)-, polychlorinated biphenyls (PCB)- and mercury (Hg)-conta...
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Article
Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study
Adiponectin is a circulating peptide derived from adipose tissue. It mediates its insulin-sensitising and anti-atherogenic effects on target tissues through two known receptors, adiponectin receptors 1 and 2 (...
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Article
Improved fibrinolysis by an intensive lifestyle intervention in subjects with impaired glucose tolerance. The Finnish Diabetes Prevention Study
The aim of this study was to investigate the effects of lifestyle intervention on the levels of plasminogen activator inhibitor (PAI-1) and fibrinogen in subjects participating in the Finnish Diabetes Preventi...
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Article
Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study
Genetic variation in leptin receptor (LEPR) gene has been reported to associate with insulin and glucose metabolism and adiposity in different study settings and various populations. We wanted to evaluate the ass...
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Article
Association between a deletion/insertion polymorphism in the α2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study
Impaired insulin secretion has a strong genetic component. In this study we investigated whether the 12Glu9 polymorphism in the gene encoding the α2B-adrenergic receptor (ADRA2B) is associated with insulin secret...
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Article
Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes.
Type 2 diabetes is a complex disorder with strong heritability. The aim of our study was to investigate whether common polymorphisms in the genes regulating the early insulin signalling pathway (insulin; A-23T, i...
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Article
Body size and substrate association of littoral insects in relation to vegetation structure
Variation in substrate association types and maximum size of aquatic insects were studied in a vegetated littoral zone of three lake basins. The basins differed from each other in trophic status, biomass of be...
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Article
Health-related quality of life in type 1 diabetes without or with symptoms of long-term complications
Objective: To measure subjective health-related quality of life (HRQoL) of patients with type 1 diabetes and describe the influence of symptoms of diabetes-related long-term complications on HRQoL. Methods: The ...
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Article
Speech sounds learned by slee** newborns
It is not yet clear whether humans are able to learn while they are slee**1,2. Here we show that full-term human newborns can be taught to discriminate between similar vowel sounds when they are fast asleep. It...
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Article
Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland Study design and 1-year interim report on the feasibility of the lifestyle intervention programme
Aims/hypothesis. The aim of the Diabetes Prevention Study is to assess the efficacy of an intensive diet-exercise programme in preventing or delaying Type II (non-insulin-dependent) diabetes mell...
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Article
Auditory and somatosensory event-related brain potentials in early blind humans
Previous event-related potential (ERP) studies have suggested a possible participation of the visual cortex of the blind in auditory processing. In the present study, somatosensory and auditory ERPs of blind a...
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Article
Cardiac rehabilitation and return to work after coronary artery bypass surgery
The work situation of 66 male patients who underwent elective coronary artery bypass surgery (CABS) and who had been randomly allocated to receive cardiac rehabilitation (group R) was compared with the work si...
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Article
Quality of life during rehabilitation after coronary artery bypass surgery
The effect of a three-phase comprehensive rehabilitation programme on the quality of life during the first postoperative year after coronary artery bypass surgery was studied in 205 male patients randomly allo...
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Article
Return of thermal sensitivity in musculocutaneous flaps A psychophysical study of flaps used for breast reconstruction after cancer
The recovery of cold, warm and heat pain sensitivity in musculocutaneous latissimus dorsi flaps (over silicone protheses) was studied in 17 patients 8 months to 5 years 8 months postoperatively. Control measur...
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Article
Mechanical sensibility of the sole of the foot determined with vibratory stimuli of varying frequency
The mechanoreceptive properties of the sole of the foot were determined by measuring the detection thresholds to vibratory stimuli of 20, 80, and 240 Hz frequency and 300 ms duration. The thresholds were measu...
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Chapter
Touch and Thermal Sensations: Psychophysical Observations and Unit Activity in Human Skin Nerves
The method of microelectrode recording from human peripheral nerves (Hagbarth and Vallbo, 1967) has proved to be useful in the analysis of the peripheral neural basis of the cutaneous sensations. At the presen...
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Article
Characteristics of single mechanoreceptive fibres innervating hairy skin of the human hand
Unit activity was recorded percutaneously by microelectrodes from 69 nerve fibres innervating the hairy skin of the back of the hand in 6 awake human subjects. Twelve fibres had no receptive field on the skin,...
