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Article
Prevalence of obesity was related to HLA-DQ in 2–4-year-old children at genetic risk for type 1 diabetes
Body size is postulated to modulate type 1 diabetes as either a trigger of islet autoimmunity or an accelerator to clinical onset after seroconversion. As overweight and obesity continue to rise among children...
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Article
Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk
The aim of this study was to compare the frequency of human leukocyte antigen (HLA) genotypes in 1–18-year-old patients with type 1 diabetes newly diagnosed in 1986–1987 (n = 430), 1996–2000 (n = 342) and in 2003...
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Article
Relationship between increased relative birthweight and infections during pregnancy in children with a high-risk diabetes HLA genotype
Children with high-risk type 1 diabetes HLA genotype have increased risk of high relative birthweight (HrBW), while cord blood islet autoantibodies decrease the risk. As gestational infections may affect offsp...
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Article
Diabetes-associated HLA genotypes affect birthweight in the general population
The aim of our study was to test the hypothesis that HLA genotypes conferring risk of diabetes, cord blood autoantibodies, or both are associated with increased birthweight.