11 Result(s)

Article

Does a fish-oil-containing lipid emulsion improve liver function in comparison with a soybean oil lipid emulsion?

J Linke, H Topp, I Mueller, S Bark, N Mertes, H Grimm, P Singer, J Shaffer in Critical Care (2010)

Article

76 DETERMINATION OF WHOLE-BODY DEGRADATION RATES OF mRNA IN VARIOUS MAMMALS BY MEASURING 7-METHYLCUANINE AND 8-HYDROXY-7-METHYLCUANINE IN URINE

We have developed a noninvasive method for determining the whole-body degradation rates of cytoplasmic tRNA, rRNA and mRNA by measuring specific nearly quantitatively excreted modified RNA-catabolites (ribonuc...

G Schöch, H Topp, K Kikillus, G Heller-Schöch in Pediatric Research (1991)

Article

78 THE WHOLE BODY TURNOVER RATES OF rRNA AND tRNA ARE CORRELATED WITH THE BASAL METABOLIC RATE IN MAMMALS OF DIFFERENT SIZE

We have developed a noninvasive method to determine whole body turnover rates of tRNA, rRNA and mRNA in mammals by measuring specific, quantitatively excreted modified RNA catafaolites (nucleosides, nucleobase...

G Schoch, H Topp, S Fenselau, O Jöhren, E Fuchs, D Güdeken… in Pediatric Research (1990)

Article

NONINVASIVE ASSESSMENT OF tRNA-, rRHA- AND mRNA-TURNOVER: COMPARATIVE HUMAN AND ANIMAL EXPERIMENTS

We have shown that whole-body turnover of tRNA, rRNA and mRNA in man can be determined by measuring the excretion of specific modified RNA catabolites (Sander et al (1986) Clin Sci 71: 367-374). Our method is ...

G Schöch, H Topp, G Sander, E Fuchs, A Held, G Heller-Schöch in Pediatric Research (1989)

Article

NONINVASIVE URINARY INDICATORS OF CATABOLISM INVESTIGATED BY EXPERIMENTAL FOOD DEFICIENCY IN RATS

We aim at measuring whole-body metabolic activity, especially metabolic imbalance caused e.g. by hunger (Schöch et al, ESPGAN 1988, Ped Res 24: 419). Particularly sensitive indicators of metabolic stress are t...

G Schöch, A Held, G Sander, H Topp, G Heller-Schöch in Pediatric Research (1989)

Article

88 INFLUENCE OF FOOD RESTRICTION ON URINARY EXCRETION OF MODIFIED RNA CATABOLITES AND OF 3-METHYLHISTIDINE IN RELATION TO NITROGEN BALANCE IN GROWING RATS

Our aim is the development of noninvasive methods for assessing the nutritional and metabolic statue. For this purpose we developed HPLC methods to selectively measure the turnover of rRNA (from urinary pseudo...

G Schöch, A Held, H Topp, G Heller-Schöch, G Sander in Pediatric Research (1988)

Article

56 INRLLUEMCE OF FOOD RESTRICTION AMD OF LOW-PROTEIN DIET ON URINARY EXCRETION OF MODIFIED RNA CATABOLITES AND OF 3-METHULHISTIDINE (M³HIS) IN RELATION TO N-BALANCE IN GROWING RATS

For assessing the nutritional and metabolic status in man, we have shown in man and animals that by measuring quantitatively excreted urinary modified RNA-catabolites the whole-body turnover of tRNA (from t⁶A, N⁶

G Schöch, A Held, H Topp, G Heller-Schöch, G Sander in Pediatric Research (1988)

Article

88. NONINVASIVE ASSESSMENT OF WHOLE-BODY METABOLIC RATES IN RATS, PRETERM INFANTS AND ADULTS USING RNA CATABOLITES IN URINE

For assessing the efficiency of nutritional supply, determination of whole-body metabolic activity, exemplified by measurements of protein turnover, are becoming more and more important. However, both techniqu...

G Schöch, G Sander, H Topp, G Heller-Schöch in Pediatric Research (1987)

Article

WHOLE-BODY RNA TURNOVER IN PRETERM INFANTS AND ADULTS IS QUANTITATIVELY LINKED TO MUSCLE PROTEIN TURNOVER

Whole-body metabolic activity can be determined using noninvasive markers. Thus, urinary 3-methylhystidine has been shown to represent whole-body turnover of actin + myosin enabling calculation of muscle prote...

G Schöch, G Sander, J Hülsemann, H Topp, G Heller-Schöch in Pediatric Research (1985)