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ProPSA and the Prostate Health Index as predictive markers for aggressiveness in low-risk prostate cancer—results from an international multicenter study

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  1. Article

    Open Access

    EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205

    Expression of epithelial cell adhesion molecule (EpCAM) is deregulated in epithelial malignancies. Beside its role in cell adhesion, EpCAM acts as signalling molecule with tumour-promoting functions. Thus, EpC...

    P Massoner, T Thomm, B Mack, G Untergasser, A Martowicz… in British Journal of Cancer (2014)

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  2. Article

    Open Access

    Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer

    The TMPRSS2-ERG gene fusion resulting in ERG overexpression has been found in around 50% of prostate cancers (PCa) and is a very early event in tumorigenesis. Most studies have reported on selected surgical cohor...

    G Schaefer, J-M Mosquera, R Ramoner, K Park… in Prostate Cancer and Prostatic Diseases (2013)

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  3. Article

    Open Access

    Insulin-like growth factors and insulin control a multifunctional signalling network of significant importance in cancer

    Insulin-like growth factor (IGF) and insulin (INS) proteins regulate key cellular functions through a complex interacting multi-component molecular network, known as the IGF/INS axis. We describe how dynamic a...

    P Massoner, M Ladurner-Rennau, I E Eder, H Klocker in British Journal of Cancer (2010)

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  4. Article

    Erratum: Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor

    Correction to: Cancer Gene Therapy (2002) 9, 117–125; doi:10.1038/sj.cgt.7700416 The authors have noticed an error in the ‘Materials and methods’ section, where the sequence of the antisense ODNas750/15 target...

    I E Eder, J Hoffmann, H Rogatsch, G Schäfer, D Zopf, G Bartsch… in Cancer Gene Therapy (2007)

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  5. Article

    Open Access

    Androgen receptor protein is down-regulated by basic fibroblast growth factor in prostate cancer cells

    Interactions between polypeptide growth factors and the androgen receptor (AR) are important for regulation of cellular events in carcinoma of the prostate. Basic fibroblast growth factor (bFGF), the prototype...

    M V Cronauer, C Nessler-Menardi, H Klocker, K Maly, A Hobisch… in British Journal of Cancer (2000)

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  6. Article

    Open Access

    Switch from antagonist to agonist of the androgen receptor blocker bicalutamide is associated with prostate tumour progression in a new model system

    Advanced prostate cancer is treated by androgen ablation and/or androgen receptor (AR) antagonists. In order to investigate the mechanisms relevant to the development of therapy-resistant tumours, we establish...

    Z Culig, J Hoffmann, M Erdel, I E Eder, A Hobisch, A Hittmair… in British Journal of Cancer (1999)

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