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Article
Open AccessImpact of the COVID-19 Pandemic on Older People’s Loneliness: Findings from a Longitudinal Study between 2019 and 2021 among Older Home-Dwellers in Finland
To investigate the change in feelings of loneliness among Finnish community-dwelling older people from before the COVID-19 pandemic in 2019 to during the pandemic in 2021. Moreover, we explore the changes in o...
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Article
Open AccessThe biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis
Dysbiotic intestinal and oral microbiota have been implicated in the pathogenesis of rheumatoid arthritis (RA), but the mechanisms how microbiota could impact disease activity have remained elusive. The aim of...
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Article
Open AccessRelationship between frailty, nutrition, body composition, quality of life, and gender in institutionalized older people
Our aim was to explore the relationship between frailty, nutrition, body composition, and how gender modifies this relationship among long-term care facility residents. We further investigated how body composi...
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Article
Open AccessImmunogenicity of subcutaneous TNF inhibitors and its clinical significance in real-life setting in patients with spondyloarthritis
Considerable proportion of patients with SpA have been immunized to the subcutaneous anti-TNF drug they are using. Concomitant use of MTX protects from immunization, whereas SASP does not. Patients with SpA us...
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Article
Open AccessSymptom burden in community-dwelling older people: temporal trends in the Helsinki Aging Study
Changes in older people’s symptoms across recent decades have not been investigated.
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Article
Open AccessPrevalence of Musculoskeletal Pain and Analgesic Treatment Among Community-Dwelling Older Adults: Changes from 1999 to 2019
Pain is undertreated in older populations. At the same time, increased use of opioids is of concern in the Western world.
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Article
Symptom Burden Is Associated with Psychological Wellbeing and Mortality in Older Adults
Over half of outpatient visits are due to physical symptoms; yet, the significance of symptoms in relation to older people’s wellbeing and prognosis has gained very little research attention.
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Article
Open AccessRelationship between Anticholinergic Burden and Health-Related Quality of Life among Residents in Long-Term Care
Anticholinergic burden defined by the Anticholinergic Risk Scale (ARS) has been associated with cognitive and functional decline. Associations with health-related quality of life (HRQoL) have been scarcely stu...
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Article
Open AccessAssociations Between Nutritional Status, Frailty and Health-Related Quality of Life Among Older Long-Term Care Residents in Helsinki
The aim of this study was to examine how nutritional status modifies the association between frailty and health-related quality of life (HRQoL) among older nursing home residents. We also investigated how resi...
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Article
Burden of Oral Symptoms and Health-Related Quality of Life in Long-Term Care Settings in Helsinki, Finland
Poor oral health may complicate eating and deteriorate nutritional status. However, little is known about how the burden of oral symptoms (OS) is associated with the health-related quality of life (HRQoL) of v...
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Open AccessAssociations Between Nutritional Status and Health-Related Quality of Life Among Long-Term Care Residents in Helsinki
We evaluated the associations between nutritional status and health-related quality-of-life (HRQoL) among older long-term care residents in Helsinki.
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Article
Open AccessMarked deterioration in the quality of life of patients with idiopathic pulmonary fibrosis during the last two years of life
Idiopathic pulmonary fibrosis (IPF) is a chronic disease with a high symptom burden and poor survival that influences patients’ health-related quality of life (HRQOL). We aimed to evaluate IPF patients’ sympto...
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Article
Increased Mortality Despite Successful Multifactorial Cardiovascular Risk Reduction in Healthy Men: 40-Year Follow-Up of the Helsinki Businessmen Study Intervention Trial
In a 5-year multifactorial risk reduction intervention for healthy men with at least one cardiovascular disease (CVD) risk factor, mortality was unexpectedly higher in the intervention than the control group d...
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Open AccessFrequent pain in older people with and without diabetes – Finnish community based study
The association between pain and diabetes in older people has been largely unexplored. The aim of this survey was to analyze the prevalence and characteristics of pain among Finnish men and women 65 or older w...
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Article
Incidence of inflammatory joint diseases in Finland: results from a population-based epidemiological study
The objective of the study was to assess the incidence of inflammatory joint diseases and possible environmental factors contributing to their occurrence in a defined population in Finland. All rheumatologists...
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Article
The effect of cryotherapy on total antioxidative capacity in patients with active seropositive rheumatoid arthritis
Patients with rheumatoid arthritis (RA) have increased oxidative stress, decreased antioxidant levels, and impaired antioxidant capacity. Cold treatments are used to relieve joint inflammation and pain. Theref...
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Article
Erratum: Association between diet quality measured by the Healthy Food Intake Index and later risk of gestational diabetes—a secondary analysis of the RADIEL trial
Correction to: European Journal of Clinical Nutrition (2017) 71, 555–557; doi:10.1038/ejcn.2016.275; published online 1 February 2017 Since the publication of this paper, the authors have noticed an error in t...
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Association between diet quality measured by the Healthy Food Intake Index and later risk of gestational diabetes—a secondary analysis of the RADIEL trial
The aim of this study was to find the association between adherence to the Nordic Nutrition Recommendations (NNR) and glucose metabolism. Participants were 137 pregnant obese women or women with a history of g...
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Article
Costs of diabetes medication among male former elite athletes in later life
Regular physical activity plays a major role, in both prevention and treatment of type 2 diabetes. Less is known whether vigorous physical activity during young adulthood is associated with costs of diabetes m...
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Article
Effect of progressive high-impact exercise on femoral neck structural strength in postmenopausal women with mild knee osteoarthritis: a 12-month RCT
It is uncertain whether subjects with mild knee osteoarthritis, and who may be at risk of osteoporosis, can exercise safely with the aim of improving hip bone strength. This RCT showed that participating in a ...
