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  1. Article

    Open Access

    The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis

    Dysbiotic intestinal and oral microbiota have been implicated in the pathogenesis of rheumatoid arthritis (RA), but the mechanisms how microbiota could impact disease activity have remained elusive. The aim of...

    J. Parantainen, G. Barreto, R. Koivuniemi, H. Kautiainen in Arthritis Research & Therapy (2022)

  2. Article

    Open Access

    Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

    Somatic mutations contribute to tumorigenesis. Although these mutations occur in all proliferating cells, their accumulation under non-malignant conditions, such as in autoimmune disorders, has not been invest...

    P. Savola, T. Kelkka, H. L. Rajala, A. Kuuliala, K. Kuuliala in Nature Communications (2017)

  3. No Access

    Article

    Causes of death in patients with rheumatoid arthritis autopsied during a 40-year period

    We studied causes of death (CoDs) between 1952 and 1991 assessed by a clinician before autopsy and then determined at autopsy by a pathologist in 369 subjects with rheumatoid arthritis (RA) and 370 subjects wi...

    R. Koivuniemi, L. Paimela, R. Suomalainen, H. Piirainen in Rheumatology International (2008)

  4. No Access

    Article

    Juvenile Chronic Arthritis in Adult Life: A Study of Long-term Outcome in Patients with Juvenile Chronic Arthritis or Adult Rheumatoid Arthritis

    We compared the prognostic factors and outcome of 30 patients with juvenile chronic arthritis (JCA) extending into adult life with those of 30 patients with adult rheumatoid arthritis (RA) at a university adu...

    R. Koivuniemi, M. Leirisalo-Repo in Clinical Rheumatology (1999)