77 Result(s)

Article

In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans

Currently available vaccines against leptospirosis are of low efficacy, have an unacceptable side-effect profile, do not induce long-term protection, and provide no cross-protection against the different serov...

Hong-Liang Yang, Yong-Zhang Zhu, **-Hong Qin, ** He, Xu-Cheng Jiang… in BMC Genomics (2006)

Article

Genetic diversity among major endemic strains of Leptospira interrogans in China

Leptospirosis is a world-widely distributed zoonosis. Humans become infected via exposure to pathogenic Leptospira spp. from contaminated water or soil. The availability of genomic sequences of Leptospira interro...

** He, Yue-Ying Sheng, Yao-Zhou Shi, **u-Gao Jiang, **-Hong Qin… in BMC Genomics (2007)

Article

Transplantation of marrow stromal cells to rescue retinal cells in SI-induced retinal degeneration in rats

Yuan Guan, Lu Cui, Yuanyuan Gong, Caihong **a, Naihe **g, Yalan Wu… in Cell Research (2008)

Article

Development of O-antigen gene cluster-specific PCRs for rapid ty** six epidemic serogroups of Leptospira in China

Leptospira is the causative agent of leptospirosis. The O-antigen is the distal part of the lipopolysaccharide, which is a key component of outer membrane of Gram-negative bacteria and confers serological specifi...

Cheng-Song Cai, Yong-Zhang Zhu, Yi Zhong, **ao-Fang **n, **u-Gao Jiang… in BMC Microbiology (2010)

Article

Accumulation of phenanthrene by roots of intact wheat (Triticum acstivnmL.) seedlings: passive or active uptake?

Polycyclic aromatic hydrocarbons (PAHs) are of particular concern due to their hydrophobic, recalcitrant, persistent, potentially carcinogenic, mutagenic and toxic properties, and their ubiquitous occurrence i...

**n-Hua Zhan, Heng-Liang Ma, Li-**ang Zhou, Jian-Ru Liang… in BMC Plant Biology (2010)

Article

Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

The virulence-attenuated Leptospira interrogans serovar Lai strain IPAV was derived by prolonged laboratory passage from a highly virulent ancestral strain isolated in China. We studied the genetic variations of ...

Yi Zhong, **ao Chang, **ng-Jun Cao, Yan Zhang, Huajun Zheng, Yongzhang Zhu… in Cell Research (2011)

Article

Improved expression of secretory and trimeric proteins in mammalian cells via the introduction of a new trimer motif and a mutant of the tPA signal sequence

Ideal immunogenicity in antigens is a prerequisite to eliciting a sufficiently strong immune and memory response via either DNA or protein vaccines. To improve immunogenicity, efforts have focused on high-leve...

Jia-Ye Wang, Wen-Ting Song, Yan Li… in Applied Microbiology and Biotechnology (2011)

Article

Isolation and characterization of ZZ1, a novel lytic phage that infects Acinetobacter baumannii clinical isolates

Acinetobacter baumannii, a significant nosocomial pathogen, has evolved resistance to almost all conventional antimicrobial drugs. Bacteriophage therapy is a potential alternative treatment for multidrug-resistan...

**g **, Zhen-Jiang Li, Shu-Wei Wang, Shan-Mei Wang, De-Hai Huang… in BMC Microbiology (2012)

Article

Molecular map** of the Pi2/9 allelic gene Pi2-2 conferring broad-spectrum resistance to Magnaporthe oryzae in the rice cultivar Jefferson

Utilization of broad-spectrum resistance (R) genes is an effective and economical strategy to control the fungal pathogen Magnaporthe oryzae, the causal agent of the rice blast disease. Among the cloned blast res...

Nan Jiang, Zhiqiang Li, Jun Wu, Yue Wang, Liqun Wu, Suhua Wang, Dan Wang, Ting Wen… in Rice (2012)

Article

Daphmacrodins A and B, alkaloids from Daphniphyllum macropodum

Two new daphnicyclidin-type Daphniphyllum alkaloids, daphmacrodins A and B (1 and 2) were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopi...

Ming-Ming Cao, Hong-** He, Yu-Cheng Gu… in Natural Products and Bioprospecting (2013)

Article

A functional variant in the cystathionine β-synthase gene promoter significantly reduces congenital heart disease susceptibility in a Han Chinese population

Homocysteine is an independent risk factor for various cardiovascular diseases. There are two ways to remove homocysteine from embryonic cardiac cells: remethylation to form methionine or transsulfuration to f...

Jian-Yuan Zhao, Xue-Yan Yang, Kai-Hu Shi, Shu-Na Sun, Jia Hou, Zhi-Zhou Ye… in Cell Research (2013)

Article

Treeline dynamics in response to climate change in the Min Mountains, southwestern China

Abies faxoniana is the dominant plant species of the forest ecosystem on the eastern edge of Qinghai-Tibet Plateau, where the treeline is strongly defined by climate. The tree-ring chronologies and age structure ...

Zhi-Jiang Zhao, Guo-Zhen Shen, Liu-Yi Tan, Dong-Wei Kang… in Botanical Studies (2013)

Article

Ecological Risks Assessment and Pollution Source Identification of Trace Elements in Contaminated Sediments from the Pearl River Delta, China

Sediments from 14 stations in the Foshan Waterway, a river crossing the industrial district of Guangdong Province, South China, were sampled and subsequently analyzed. The 14 stations were selected for the pol...

Feng Li, **ang-yun Zeng, Chang-hua Wu, Zhi-peng Duan… in Biological Trace Element Research (2013)

Article

Global analysis of the differentially expressed miRNAs of prostate cancer in Chinese patients

Our recent study showed the global physiological function of the differentially expressed genes of prostate cancer in Chinese patients was different from that of other non-Chinese populations. microRNA are est...

Hui-chan He, Zhao-dong Han, Qi-shan Dai, **ao-hui Ling, **n Fu… in BMC Genomics (2013)

Article

High throughput sequencing of two celery varieties small RNAs identifies microRNAs involved in temperature stress response

MicroRNAs (miRNAs) are small, non-coding RNAs of 20 to 24 nucleotides that regulate gene expression and responses to biotic and abiotic stress. Till now, no reports have previously been published concerning mi...

Meng-Yao Li, Feng Wang, Zhi-Sheng Xu, Qian Jiang, **g Ma, Guo-Fei Tan… in BMC Genomics (2014)

Article

Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis

Amycolatopsis orientalis is the type species of the genus and its industrial strain HCCB10007, derived from ATCC 43491, has been used for large-scale production of the vital antibiotic vancomycin. However, to dat...

Li Xu, He Huang, Wei Wei, Yi Zhong, Biao Tang, Hua Yuan, Li Zhu… in BMC Genomics (2014)

Article

IRF4 is a novel mediator for neuronal survival in ischaemic stroke

Neuroprotection following ischaemic stroke is driven by the interplay between regulatory transcription factors and endogenous protective factors. IRF4, a member of the interferon regulatory factor (IRF) family...

S Guo, Z-Z Li, D-S Jiang, Y Y Lu, Y Liu, L Gao, S-M Zhang… in Cell Death & Differentiation (2014)

Article

Genome organisation of the Acinetobacter lytic phage ZZ1 and comparison with other T4-like Acinetobacter phages

Phage ZZ1, which efficiently infects pathogenic Acinetobacter baumannii strains, is the fifth completely sequenced T4-like Acinetobacter phage to date. To gain a better understanding of the genetic characteristic...

**g **, Zhen-Jiang Li, Shu-Wei Wang, Shan-Mei Wang, Song-Jian Chen… in BMC Genomics (2014)

Article

Chemical Constituents from the Stems of Manihot esculenta

Two new compounds, maniesculentins A (1) and B (6), together with four known ones were isolated from the stems of Manihot esculenta Crantz. The structures of the new compounds were elucidated by extensive spectro...

Ya-Mei Pan, Yu Zhang, **ao-Nan Wang, He-** Chen… in Natural Products and Bioprospecting (2015)

Article

Genome-wide association study for flowering time, maturity dates and plant height in early maturing soybean (Glycine max) germplasm

Soybean (Glycine max) is a photoperiod-sensitive and self-pollinated species. Days to flowering (DTF) and maturity (DTM), duration of flowering-to-maturity (DFTM) and plant height (PH) are crucial for soybean ada...

Jiao** Zhang, Qijian Song, Perry B Cregan, Randall L Nelson, **anzhi Wang… in BMC Genomics (2015)