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  1. Article

    Open Access

    Molecular basis of Tousled-Like Kinase 2 activation

    Tousled-like kinases (TLKs) are required for genome stability and normal development in numerous organisms and have been implicated in breast cancer and intellectual disability. In humans, the similar TLK1 and...

    Gulnahar B. Mortuza, Dario Hermida, Anna-Kathrine Pedersen… in Nature Communications (2018)

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    Article

    Structure of p15PAF–PCNA complex and implications for clamp sliding during DNA replication and repair

    The intrinsically disordered protein p15PAF regulates DNA replication and repair by binding to the proliferating cell nuclear antigen (PCNA) sliding clamp. We present the structure of the human p15PAF–PCNA comple...

    Alfredo De Biasio, Alain Ibáñez de Opakua, Gulnahar B. Mortuza… in Nature Communications (2015)

  3. Article

    Open Access

    XTACC3–XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

    chTOG is a conserved microtubule polymerase that catalyses the addition of tubulin dimers to promote microtubule growth. chTOG interacts with TACC3, a member of the transforming acidic coiled-coil (TACC) famil...

    Gulnahar B. Mortuza, Tommaso Cavazza, Maria Flor Garcia-Mayoral… in Nature Communications (2014)

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  4. Article

    Erratum: High-resolution structure of a retroviral capsid hexameric amino-terminal domain

    Nature 431, 481–485 (2004). In this Letter, the following sentence should have appeared after the aunamethor's email address: ‘Coordinates and structure factors have been deposited in the Protein Data Bank und...

    Gulnahar B. Mortuza, Lesley F. Haire, Anthony Stevens, Stephen J. Smerdon… in Nature (2004)

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  5. No Access

    Article

    High-resolution structure of a retroviral capsid hexameric amino-terminal domain

    Retroviruses are the aetiological agents of a range of human diseases including AIDS and T-cell leukaemias. They follow complex life cycles, which are still only partly understood at the molecular level. Matur...

    Gulnahar B. Mortuza, Lesley F. Haire, Anthony Stevens, Stephen J. Smerdon… in Nature (2004)