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C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery

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  1. Article

    Aerobic exercise capacity in long-term survivors of critical illness: secondary analysis of the post-EPaNIC follow-up study

    To evaluate aerobic exercise capacity in 5-year intensive care unit (ICU) survivors and to assess the association between severity of organ failure in ICU and exercise capacity up to 5-year follow-up.

    Nathalie Van Aerde, Philippe Meersseman, Yves Debaveye in Intensive Care Medicine (2021)

  2. Article

    Intensive care unit acquired muscle weakness in COVID-19 patients

    Nathalie Van Aerde, Greet Van den Berghe, Alexander Wilmer in Intensive Care Medicine (2020)

  3. Article

    ICU-acquired weakness

    Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk factors, short- and long-term conseq...

    Ilse Vanhorebeek, Nicola Latronico, Greet Van den Berghe in Intensive Care Medicine (2020)

  4. Article

    Open Access

    Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study

    Increased systemic cortisol availability during adult critical illness is determined by reduced binding-proteins and suppressed breakdown rather than elevated ACTH. Dynamics, drivers and prognostic value of hy...

    An Jacobs, Inge Derese, Sarah Vander Perre, Pieter J. Wouters in Intensive Care Medicine (2020)

  5. Article

    Less is more in critical care is supported by evidence-based medicine

    Catherine L. Auriemma, Greet Van den Berghe, Scott D. Halpern in Intensive Care Medicine (2019)

  6. Article

    Open Access

    ACTH and cortisol responses to CRH in acute, subacute, and prolonged critical illness: a randomized, double-blind, placebo-controlled, crossover cohort study

    Low plasma ACTH in critically ill patients may be explained by shock/inflammation-induced hypothalamus-pituitary damage or by feedback inhibition exerted by elevated plasma free cortisol. One can expect augmen...

    Bram Peeters, Philippe Meersseman, Sarah Vander Perre in Intensive Care Medicine (2018)

  7. Article

    Open Access

    Adrenocortical function during prolonged critical illness and beyond: a prospective observational study

    For patients suffering from prolonged critical illness, it is unknown whether and when the hypothalamus–pituitary–adrenal axis alterations recover, and to what extent adrenocortical function parameters relate ...

    Bram Peeters, Philippe Meersseman, Sarah Vander Perre in Intensive Care Medicine (2018)

  8. Article

    Correction to: Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017

    To update the 2008 consensus statements for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients

    Djillali Annane, Stephen M. Pastores, Bram Rochwerg, Wiebke Arlt in Intensive Care Medicine (2018)

  9. Article

    Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM)

    To provide a narrative review of the latest concepts and understanding of the pathophysiology of critical illness-related corticosteroid insufficiency (CIRCI).

    Djillali Annane, Stephen M. Pastores, Wiebke Arlt in Intensive Care Medicine (2017)

  10. Article

    Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017

    To update the 2008 consensus statements for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients.

    Djillali Annane, Stephen M. Pastores, Bram Rochwerg, Wiebke Arlt in Intensive Care Medicine (2017)

  11. Article

    Open Access

    The intensive care medicine research agenda in nutrition and metabolism

    The objectives of this review are to summarize the current practices and major recent advances in critical care nutrition and metabolism, review common beliefs that have been contradicted by recent trials, hig...

    Yaseen M. Arabi, Michael P. Casaer, Marianne Chapman in Intensive Care Medicine (2017)

  12. Article

    The ICM research agenda on intensive care unit-acquired weakness

    We present areas of uncertainty concerning intensive care unit-acquired weakness (ICUAW) and identify areas for future research. Age, pre-ICU functional and cognitive state, concurrent illness, frailty, and he...

    Nicola Latronico, Margaret Herridge, Ramona O. Hopkins in Intensive Care Medicine (2017)

  13. Article

    What’s new in glucose control in the ICU?

    Greet Van den Berghe in Intensive Care Medicine (2013)

  14. Article

    Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care

    Jeremy J. Cordingley, Dirk Vlasselaers, Natalie C. Dormand in Intensive Care Medicine (2009)

  15. Article

    Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?

    Björn Ellger, Lies Langouche, Milan Richir, Yves Debaveye in Intensive Care Medicine (2008)

  16. Article

    Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?

    Björn Ellger, Lies Langouche, Milan Richir, Yves Debaveye in Intensive Care Medicine (2008)