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Article
Open AccessOxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking
As opioid-related fatalities continue to rise, the need for novel opioid use disorder (OUD) treatments could not be more urgent. Two separate hypothalamic neuropeptide systems have shown promise in preclinical...
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Article
Open AccessA common limiter circuit for opioid choice and relapse identified in a rodent addiction model
Activity in numerous brain regions drives heroin seeking, but no circuits that limit heroin seeking have been identified. Furthermore, the neural circuits controlling opioid choice are unknown. In this study, ...
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Article
Open AccessPrefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval
The prefrontal cortex is an important regulator of fear expression in humans and rodents. Specifically, the rodent prelimbic (PL) prefrontal cortex drives fear expression during both encoding and retrieval of ...
