Skip to main content

and
  1. No Access

    Article

    The sinking platform test: a novel paradigm to measure persistence in animal models

    Persistence is the propensity to maintain goal-directed actions despite adversities. While this temperamental trait is crucial to mitigate depression risk, its neurobiological foundations remain elusive. Devel...

    Gabriele Floris, Sean C. Godar, Giulia Braccagni in Neuropsychopharmacology (2024)

  2. No Access

    Article

    Elevated levels of serotonin 5-HT2A receptors in the orbitofrontal cortex of antisocial individuals

    Antisocial behavior (ASB) is characterized by frequent violations of the rights and properties of others, as well as aggressive conduct. While ample evidence points to a critical role of serotonin in the emoti...

    Giulia Braccagni, Simona Scheggi in European Archives of Psychiatry and Clinic… (2023)

  3. Article

    Open Access

    Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences

    The social motivational theory of autism spectrum disorder (ASD) focuses on social anhedonia as key causal feature of the impaired peer relationships that characterize ASD patients. ASD prevalence is higher in...

    Simona Scheggi, Francesca Guzzi, Giulia Braccagni in Molecular Autism (2020)