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From Molecular Biology to Science Diplomacy: A Long and Winding Road
As young kids we view science as a fascinating world of breakthrough discoveries, and it was probably this childish idea that drove me into choosing biological sciences as a field of study. Like all aspects of...
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Article
Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice
Several studies highlighted a correlation between folic acid deficiency and high plasma homocysteine concentration, considered a risk factor for multifactorial diseases. Natural folates represent an emerging a...
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Article
Open AccessImpact of supplementation with a food-derived microbial community on obesity-associated inflammation and gut microbiota composition
Obesity is a complex pathology associated with dysbiosis, metabolic alterations, and low-grade chronic inflammation promoted by immune cells, infiltrating and populating the adipose tissue. Probiotic supplemen...
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Article
Open AccessPropelling the paradigm shift from reductionism to systems nutrition
The complex physiology of living organisms represents a challenge for mechanistic understanding of the action of dietary bioactives in the human body and of their possible role in health and disease. Animal, c...
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Human nutrition, environment, and health
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Article
Zinc proteome interaction network as a model to identify nutrient-affected pathways in human pathologies
Zinc is an essential micronutrient playing fundamental roles in cellular metabolism. It acts mostly through binding a wide range of proteins, thus affecting a broad spectrum of biological processes, which incl...
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Article
The new “face-to-face” commentaries in Genes & Nutrition
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Article
Introduction to the special issue “Probiotic bacteria and human gut microbiota”
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Article
Open AccessAntibiotic resistance determinants in the interplay between food and gut microbiota
A complex and heterogeneous microflora performs sugar and lactic acid fermentations in food products. Depending on the fermentable food matrix (dairy, meat, vegetable etc.) as well as on the species compositio...
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Article
Connecting the Human Variome Project to nutrigenomics
Nutrigenomics is the science of analyzing and understanding gene–nutrient interactions, which because of the genetic heterogeneity, varying degrees of interaction among gene products, and the environmental div...
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Article
Open AccessThe Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research
Micronutrients influence multiple metabolic pathways including oxidative and inflammatory processes. Optimum micronutrient supply is important for the maintenance of homeostasis in metabolism and, ultimately, ...
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Article
From phytoestrogens to obesity and the metabolic syndrome: Health from food and food for health
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Article
The Znt4 mutation inlethal milk mice affects intestinal zinc homeostasis through the expression of other Zn transporters
The lethal milk mouse syndrome is caused by a point mutation in the zinc transporter gene ZnT4 resulting in defective zinc secretion in the milk of homozygous mutant dams. Pups of any genotype fed solely on lm...
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Article
Alkylation mutagenesis in Saccharomyces cerevisiae: lack of evidence for an adaptive response
We have found no evidence for an adaptive response for either lethality or mutagenesis following treatment of Saccharomyces cerevisiae with N-methyl-N′-nitro-N-nitrosoguanidine (MNNG). The rad6 and rad52 mutants ...
