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Article
Open AccessTime perception in astronauts on board the International Space Station
We perceive the environment through an elaborate mental representation based on a constant integration of sensory inputs, knowledge, and expectations. Previous studies of astronauts on board the International ...
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Article
Open AccessEffects of motion paradigm on human perception of tilt and translation
The effect of varying sinusoidal linear acceleration on perception of human motion was examined using 4 motion paradigms: off-vertical axis rotation, variable radius centrifugation, linear lateral translation,...
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Article
Open AccessHorizontal and Vertical Distance Perception in Altered Gravity
The perception of the horizontal and vertical distances of a visual target to an observer was investigated in parabolic flight during alternating short periods of normal gravity (1 g). microgravity (0 g), and ...
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Article
Vestibular and Sensorimotor Dysfunction During Space Flight
This paper aims to review dysfunctions in spatial orientation, cognition, gaze stabilization, and posture and locomotor control recently documented in astronauts during and immediately after both short- and lo...
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Article
Open AccessOcular Counter Rolling in Astronauts After Short- and Long-Duration Spaceflight
Ocular counter-rolling (OCR) is a reflex generated by the activation of the gravity sensors in the inner ear that stabilizes gaze and posture during head tilt. We compared the OCR measures that were obtained i...
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Article
Open AccessInternational roadmap for artificial gravity research
In this paper, we summarize the current and future research activities that will determine the requirements for implementing artificial gravity (AG) to mitigate the effects of long duration exposure to microgr...
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Article
Open AccessEye-Head Coordination in 31 Space Shuttle Astronauts during Visual Target Acquisition
Between 1989 and 1995, NASA evaluated how increases in flight duration of up to 17 days affected the health and performance of Space Shuttle astronauts. Thirty-one Space Shuttle pilots participating in 17 spac...
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Article
Open AccessOcular Reflex Phase during Off-Vertical Axis Rotation in Humans is Modified by Head-Turn-On-Trunk Position
Constant velocity Off-Vertical Axis Rotation (OVAR) imposes a continuously varying orientation of the head and body relative to gravity, which generates a modulation of horizontal (conjugate and vergence), ver...
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Article
Open AccessTowards human exploration of space: the THESEUS review series on neurophysiology research priorities
The THESEUS project (Towards Human Exploration of Space: a European Strategy), initiated within the seventh Framework Programme by the European Commission, aimed at providing a cross-cutting, life-science-base...
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Article
Open AccessImpact of patient education on chronic heart failure in primary care (ETIC): a cluster randomised trial
The Education Thérapeutique des patients Insuffisants Cardiaques (ETIC; Therapeutic Education for Patients with Cardiac Failure) trial aimed to determine whether a pragmatic education intervention in general prac...
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Article
Influence of Host-Plant Surface Chemicals on the Oviposition of the Cereal Stemborer Busseola Fusca
The chemical composition of plant surfaces plays a role in selection of host plants by herbivorous insects. Once the insect reaches the plant, these cues determine host acceptance. Laboratory studies have show...
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Article
Open AccessDysfunctional vestibular system causes a blood pressure drop in astronauts returning from space
It is a challenge for the human body to maintain stable blood pressure while standing. The body’s failure to do so can lead to dizziness or even fainting. For decades it has been postulated that the vestibular...
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Article
Short-arm centrifugation as a partially effective musculoskeletal countermeasure during 5-day head-down tilt bed rest—results from the BRAG1 study
Human centrifugation, also called artificial gravity (AG), is proposed as a combined strategy against detrimental effects of microgravity in long-term space missions. This study scrutinized human short-arm cen...
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Open AccessPatient education in chronic heart failure in primary care (ETIC) and its impact on patient quality of life: design of a cluster randomised trial
Chronic heart failure, is increasing due to the aging population and improvements in heart disease detection and management. The prevalence is estimated at ~10% of the French general practice patient populatio...
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Article
Open AccessAn integrated “omics” approach to the characterization of maize (Zea mays L.) mutants deficient in the expression of two genes encoding cytosolic glutamine synthetase
To identify the key elements controlling grain production in maize, it is essential to have an integrated view of the responses to alterations in the main steps of nitrogen assimilation by modification of gene...
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Article
Open AccessCANABIC: CANnabis and Adolescents: effect of a Brief Intervention on their Consumption – study protocol for a randomized controlled trial
Cannabis is the most consumed illegal substance in France. General practitioners (GPs) are the health professionals who are most consulted by adolescents. Brief intervention (BI) is a promising care initiative...
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Article
Space physiology II: adaptation of the central nervous system to space flight—past, current, and future studies
Experiments performed in orbit on the central nervous system have focused on the control of posture, eye movements, spatial orientation, as well as cognitive processes, such as three-dimensional visual percept...
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Maximizing information from space data resources: a case for expanding integration across research disciplines
Regulatory systems are affected in space by exposure to weightlessness, high-energy radiation or other spaceflight-induced changes. The impact of spaceflight occurs across multiple scales and systems. Explorin...
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Space Biology
Gravity provides a directional stimulus that plays an important role in basic life processes in the cell, such as biosynthesis, membrane exchange, and cell growth and development. It is likely that the growth...