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Open AccessSystematic review of the effectiveness of standalone passive countermeasures on microgravity-induced physiologic deconditioning
A systematic review of literature was conducted to evaluate the effectiveness of passive countermeasures in ameliorating the cardiopulmonary and musculoskeletal effects of gravitational unloading on humans dur...
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Open AccessAuthor Correction: Systematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight
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Open AccessCorrection: COVID-19 and its effects on endothelium in HIV-positive patients in sub-saharan Africa: cardiometabolic risk, thrombosis and vascular function (ENDOCOVID STUDY)
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Open AccessSystematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight
The validity of venous ultrasound (V-US) for the diagnosis of deep vein thrombosis (DVT) during spaceflight is unknown and difficult to establish in diagnostic accuracy and diagnostic management studies in thi...
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Open AccessEffects of whole-body vibration or resistive-vibration exercise on blood clotting and related biomarkers: a systematic review
Whole-body vibration (WBV) and resistive vibration exercise (RVE) are utilized as countermeasures against bone loss, muscle wasting, and physical deconditioning. The safety of the interventions, in terms of th...
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Open AccessRetinal venular vessel diameters are smaller during ten days of bed rest
Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during ...
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Open AccessAuthor Correction: The kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps
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Open AccessCompensatory hemodynamic changes in response to central hypovolemia in humans: lower body negative pressure: updates and perspectives
Central hypovolemia is accompanied by hemodynamic compensatory responses. Understanding the complex systemic compensatory responses to altered hemodynamic patterns during conditions of central hypovolemia—as i...
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Increased cerebral vascular resistance underlies preserved cerebral blood flow in response to orthostasis in humans on a high-salt diet
Cerebral blood flow autoregulation protects brain tissue from blood pressure variations and maintains cerebral perfusion pressure by changes in vascular resistance. High salt (HS) diet impairs endothelium-depe...
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Open AccessThe kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps
Although we have sent humans into space for more than 50 years crucial questions regarding kidney physiology, volume regulation and osmoregulation remain unanswered. The complex interactions between the renin-...
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Open AccessPathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?
The recent incidental discovery of an asymptomatic venous thrombosis (VT) in the internal jugular vein of an astronaut on the International Space Station prompted a necessary, immediate response from the space...
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Open AccessMechanical deconditioning of the heart due to long-term bed rest as observed on seismocardiogram morphology
During head-down tilt bed rest (HDT) the cardiovascular system is subject to headward fluid shifts. The fluid shift phenomenon is analogous to weightlessness experienced during spaceflight microgravity. The pu...
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Open AccessThe effect of physical activity intervention and nutritional habits on anthropometric measures in elementary school children: the health oriented pedagogical project (HOPP)
Overweight and obesity are a burden of the modern world that requires urgent action. Prevention has proven to be efficient in the fight against overweight and obesity. As many children gain excessive weight at...
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Open AccessCOVID-19 and its effects on endothelium in HIV-positive patients in sub-Saharan Africa: Cardiometabolic risk, thrombosis and vascular function (ENDOCOVID STUDY)
COVID-19 has affected almost every country in the world, especially in terms of health system capacity and economic burden. People from sub-Saharan Africa (SSA) often face interaction between human immunodefic...
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Open AccessAssessment of the impact of HIV infection and anti-retroviral treatment on the cardiometabolic health of pregnant mothers and their offspring (ARTMOMSBABES)
The risk of cardiovascular diseases (CVDs) is becoming more prevalent in pregnant women though not much data is available for pregnant women with human immunodeficiency virus (HIV). Foetoplacental vascular end...
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Open AccessIndependent influence of age on heart rate recovery after flywheel exercise in trained men and women
The present study examined whether differences in the heart rate recovery following flywheel exercise cessation were associated with differences in maximal oxygen uptake (
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Open AccessSeasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans
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Sturzrisiko, zirkadiane Rhythmen, Vagusaktivität und Melatonin
Altern ist mit einer Verringerung der Schwingungsamplitude des Tagesverlaufs von physiologischen Variablen verbunden. Die Häufigkeit von Stürzen folgt bei älteren Menschen einem Tagesgang. Darüber hinaus sind ...
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Open AccessThe prevalence of pediatric metabolic syndrome—a critical look on the discrepancies between definitions and its clinical importance
The Metabolic Syndrome (MetS) describes the clustering of cardio-metabolic risk factors—including abdominal obesity, insulin resistance, elevated blood pressure, high levels of triglycerides, and low levels of...
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Open AccessProlonged bedrest reduces plasma high-density lipoprotein levels linked to markedly suppressed cholesterol efflux capacity
Recent observations strongly connect high-density lipoproteins (HDL) function and levels with coronary heart disease outcomes and risk for infections and sepsis. To date, our knowledge of factors determining t...
