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Chapter
New Technologies to Image Tumors
The premise of this book is the importance of the tumor microenvironment (TME). Until recently, most research on and clinical attention to cancer biology, diagnosis, and prognosis were focused on the malignant...
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Protocol
Low Magnification Confocal Microscopy of Tumor Angiogenesis
Blood vessels are critical to normal mammalian development, tissue repair, and growth and treatment of cancer. Mouse research models enable mechanistic studies of blood vessels. We detail how to perfuse mice w...
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Article
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation
The human germinal centre-associated lymphoma gene is specifically expressed in germinal centre B-lymphocytes and germinal centre-derived B-cell lymphomas, but its function is largely unknown. Here we demonstr...
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Article
Open AccessApoptosis, mastocytosis, and diminished adipocytokine gene expression accompany reduced epididymal fat mass in long-standing diet-induced obese mice
Obesity is characterized by increased cell death and inflammatory reactions in the adipose tissue. Here, we explored pathophysiological alterations taking place in the adipose tissue in long-standing obesity. ...
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Article
Antitumorigenic Effect of Brain Proline Rich Polypeptide-1 in Human Chondrosarcoma
Proline rich polypeptide (PRP-1) produced by neurosecretory cells of the hypothalamus is one of the fragments of neurophysin-vasopressin-associated glycoprotein. The primary structure of the neuropeptide PRP-1...
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Article
In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines
Abstract
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Chapter
Spectral Karyoty**: New Tools for Multicolor Chromosome Analysis
Chromosome analysis is the basis for both cytogenetic research and diagnostics. The discovery that chromosomal abnormalities are aleading cause of genetic diseases, including congenital disorders and acquired ...
