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  1. No Access

    Chapter

    Minimal Residual Disease in Head and Neck Cancer and Esophageal Cancer

    Malignant epithelial tumors of the upper digestive tract are a major cause of cancer-related death worldwide. The most common of these cancers are head and neck squamous cell carcinomas (HNSCC) and esophageal ...

    Christoph Sproll, Georg Fluegen… in Biological Mechanisms of Minimal Residual … (2018)

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    Article

    Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments

    Hypoxia is a poor-prognosis microenvironmental hallmark of solid tumours, but it is unclear how it influences the fate of disseminated tumour cells (DTCs) in target organs. Here we report that hypoxic HNSCC an...

    Georg Fluegen, Alvaro Avivar-Valderas, Yarong Wang… in Nature Cell Biology (2017)