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Article
Operating algorithm and hardware implementation of sinusoidal signal parameter measurer in generator excitation circuits
A certain algorithm and hardware implementation used to measure current and voltage parameters in electric generator during excitation are considered. As is generally known, measurement time for these paramete...
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Article
Building communication channels for mobile robot control: The implementation experience
Nowadays mobile robots become loaded with information. The application conditions need installation of various sensors, machine vision systems, and detection and navigation facilities. It goes without saying t...
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Article
Radiation conditions along the perimeter and near the Russian Science Center Kurchatov Institute
The results of measurements of the dose rate from γ radiation along the perimeter, at operating gates, and near the grounds of the Russian Science Center Kurchatov Institute are presented. The computed dose is...
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Article
Radioecological studies of a construction site in Sayda Guba for long-term storage of reactor compartments
Specialists at the Russian Science Center Kurchatov Institute have performed radioecological studies on a construction site in Sayda Guba (Kol’skiy Zaliv) for long-term storage of reactor compartments. The res...
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Article
Highly efficient modification of DNA polymerase β under conditions of direct and sensitized activation of photoreactive DNAs. Modification of cell extract proteins
dUTP and dCTP derivatives containing a 4-azido-2,3,5,6-tetrafluorobenzylideneaminooxy group were incorporated into the 3′-end of the DNA primer within complexes with the DNA-matrix as analogs of natural dTTP b...
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Article
Monomers for Oligonucleotide Synthesis with Linkers Carrying Reactive Residues: II. The Synthesis of Phosphoamidites on the Basis of Uridine and Cytosine and Containing a Linker with Methoxyoxalamide Groups in Position 2′
A convenient preparative synthesis of 2′-amino-2′-deoxyuridine was developed. Starting from 2′-amino-2′-deoxyuridine and 2′-amino-2′-deoxycytidine, monomers for the phosphoamidite oligonucleotide synthesis wer...
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Article
Monomers for Oligonucleotide Synthesis with Linkers Carrying Reactive Residues: I. The Synthesis of Deoxynucleoside Derivatives with Methoxyoxalamide Groups in Heterocyclic Bases
A number of monomers for the standard phosphoamidite oligodeoxynucleotide synthesis that carry reactive methoxyoxalamide groups attached to the thymidine, 2′-deoxycytidine, and 2′-deoxyadenosine heterocyclic b...
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Article
Design and synthesis of artificial ribonucleases based on 1,4-diazabicyclo[2.2.2]octane and imidazole
The review surveys the results of our studies devoted to the design of highly efficient catalysts of hydrolysis of the phosphodiester bonds in RNA. These catalysts contain the imidazole residue in the catalyti...
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Article
Chemical Ribonucleases: 4.1 An Analysis of the Domain Structure of Chemical Ribonucleases Based on 1,4-Diazabicyclo[2.2.2]octane
Artificial ribonucleases of the ABLkCm series were synthesized. They consist of a lipophilic alkyl radical (Et, n-C14H29, or n-C15H31) А, an “RNA-binding domain” В (bisquaternary salt of 1,4-diazabicyclo[2.2.2]oc...
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Article
Reagents for Modification of Protein–Nucleic Acid Complexes: III.1Site-Specific Photomodification of Elongation Complex of DNA Polymerase β with Arylazide Derivatives of Primers Sensitized with Fluorescent ATP γ-Amides
ATP γ-amides containing in γ-N-position 1-methylpyrene, 9-methylanthracene, 10-chloro-9-methyl-anthracene, and 3-methylperylene residues were synthesized and characterized. These compounds were used as sensitizer...
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Article
Reagents for Modification of Protein–Nucleic Acid Complexes: II.1Site-Specific Photomodification of Mammalian DNA Polymerase β Complexes with Primers Extended by dCTP exo-N-Substituted Arylazido Derivatives
Substrate properties of the earlier synthesized and characterized dCTP derivatives bearing in the exo-N-position of cytosine 2-(4-azido-2,3,5,6-tetrafluorobenzoylamino)ethyl (I), 2-(2-nitro-5-azidobenzoylamino)et...
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Article
A Scanning System for the Michelson Interferometer with a Linear Motor Based on a Permanent Magnet
A scanning system for the moving mirror of the Michelson interferometer is described. The system is based on a linear motor with a ring-shaped permanent magnet. The operating velocity of the mirror is about 4 ...
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Article
Chemical ribonucleases: 3. The synthesis of organic catalysts for the phosphodiester bond hydrolysis on the basis of quaternary salts of 1,4-diazabicyclo[2.2.2]octane
On the basis of imidazole and bisquaternary salts of 1,4-diazabicyclo[2.2.2]octane, a number of highly effective catalysts of thenDm series (here,n is the number of positive charges at neutral pH values andm is t...
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Article
Reagents for addressed modification of biopolymers
Derivatives of histidine, imidazolylacetic and urocanic acids, containing anN Im-2,4-dinitrophenyl moiety and a hydroxy group were synthesized and characterized. The applicability of these reagent...
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Article
Reagents for specific modification of biopolymers
Direct nucleophilic substitution of primary and secondary amines for hydrogen in quaternary phenazinium salts containing an additional positive charge in the aliphatic part of the molecule was carried out. The...
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Article
Reagents for directed modification of biopolymers
The synthesis of new heterobifunctional reagents that are photo-activated, namely, 6-azido-1,3,4,5,7,8-hexafluoro-2-naphthoic acid (2), succinimido-6-azido-1,3,4,5,7,8-hexafluoro-2-naphthoate (3), andN-(n-butyl)-...
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Article
Reagents for specific modification of biopolymers 8. Synthesis of 2,7-diaminophenazinium salts by nucleophilic substitution of hydrogen
Direct nucleophilic substitution in quaternary 2-N-alkylacetamidophenazinium salts with primary and secondary amines can serve as a convenient method for the introduction of two different substituents under mi...
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Article
Two-component neutrino in gravitational field
The problem of the exact solutions of the Weyl equation in the presence of the gravitational field is investigated by means of an algebraic method of separation of variables. Only the diagonal metrics are take...
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Article
Diazabicycloalkanes with bridgehead nitrogen atoms. 28. Stevens rearrangement of benzodiazabicycloalkenes
Stevens rearrangement of the benzyl bromides of benzo[b]-1,4-diazabicyclo[2.2.2]octene and benzo[f]-1,5-diazabicyclo[3.2.2]-nonene occurs with expansion of the diazabicyclic fragments to form a mixture of ster...
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Article
Multichannel radiation-monitoring system with automatic data transmission through telephone network