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Article
Translocation of c-abl oncogene and PDGFB (c-sis) gene in a case of CML with 46, XY, t(22;22)
In a case of CML with a variant Philadelphia translocation (Ph1 or Ph) t (22;22) (q11;q13) in bone marrow cells and unstimulated peripheral blood cells, no cytogenetically detectable involvement of chromosome 9 w...
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Effects of fosfomycin, mesna, and sodium thiosulfate on the toxicity and antitumor activity of cisplatin
Fosfomycin and mesna were investigated in rats and mice concerning their detoxifying effects on cisplatin toxicity in comparison to sodium thiosulfate, a known protector against cisplatin nephrotoxicity. After...
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Article
Influence of mesna and cysteine on the systemic toxicity and therapeutic efficacy of activated cyclophosphamide
Presumably the coadministration of the uroprotector mesna in cyclophosphamide treatment does not influence the systemic activity of its activated metabolite. This was newly investigated in a mouse model. The LD50