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  1. Article

    High-vs low-dose cytarabine combined with interferon alfa in patients with first chronic phase chronic myeloid leukemia. A prospective randomized phase III study

    A prospective randomized phase III study was performed to evaluate whether intensified cytarabine would induce a higher response rate and longer event-free interval as compared to low-dose cytarabine in chroni...

    W. Deenik, B. van der Holt, G. E. G. Verhoef… in Annals of Hematology (2007)

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    Disseminated infection by Scedosporium Prolificans: an emerging fatality among haematology patients. Case report and review

    We describe a case of proven disseminated infection by Scedosporium prolificans in a profoundly neutropenic patient. The patient presented with a fever unresponsive to broad-spectrum antibiotics, endophthalmitis...

    J. Maertens, K. Lagrou, H. Deweerdt, I. Surmont, G. E. G. Verhoef… in Annals of Hematology (2000)

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    Lymphocyte profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: flow-cytometric characterization and analysis in a two-dimensional correlation biplot

     The distribution of 27 T-, B-, and natural killer-cell subsets in the peripheral blood of 40 patients with multiple myeloma (MM), ten patients with monoclonal gammopathy of undetermined significance (MGUS), a...

    L. E. Van den Hove, P. Meeus, A. Derom, H. Demuynck… in Annals of Hematology (1998)

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    Successful control of refractory and life-threatening autoimmune hemolytic anemia with intravenous immunoglobulins in a man with the primary antiphospholipid syndrome

     A 58-year old man with a history of hypothyroidism and primary antiphospholipid syndrome (with recurrent thromboembolic disease and therapy-refractory autoimmune thrombocytopenic purpura) presented with a lif...

    P. Vandenberghe, P. Zachee, S. Verstraete, H. Demuynck… in Annals of Hematology (1996)

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    An update on peripheral blood progenitor cell transplantation

    High-dose therapy with stem cell rescue is increasingly being used as a salvage or consolidation therapy for patients with poor-risk malignant disease. The availability of peripheral blood progenitor cells (PB...

    H. Demuynck, M. Delforge, P. Zachée, G. E. G. Verhoef… in Annals of Hematology (1995)

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    FAB classification of myelodysplastic syndromes: merits and controversies

    Guidelines for the definition and diagnosis of myelodysplasia were set out by the French-American-British Cooperative group (FAB), and the resulting framework has greatly helped the now very large number of wo...

    G. E. G. Verhoef, S. Pittaluga, C. De Wolf-Peeters, M. A. Boogaerts in Annals of Hematology (1995)

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    Risks of rhG-CSF treatment in drug-induced agranulocytosis

    Nine patients with drug-induced agranulocytosis received recombinant human granulocyte colonystimulating factor (rhG-CSF) to accelerate myeloid recovery because of life-threatening infections related to neutro...

    H. Demuynck, P. Zachée, G. E. G. Verhoef, M. Schetz… in Annals of Hematology (1995)

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    Hypercalcemia, monoclonal protein, and osteolytic bone lesions in chronic lymphocytic leukemia

    We describe a patient with a long history of typical chronic lymphocytic leukemia (CLL) who developed hypercalcemia, osteolytic bone lesions, and a monoclonal protein, all features of a secretory plasma cell d...

    M. Van de Casteele, G. E. G. Verhoef, H. Demuynck, P. Zacheé… in Annals of Hematology (1994)

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    Recombinant human erythropoietin for the treatment of anemia in the myelodysplastic syndromes: A clinical and erythrokinetic assessment

    The clinical and ferrokinetic effects of escalating doses of subcutaneously administered recombinant human erythropoietin (rh-EPO) were studied in ten patients with myelodysplastic syndromes and severe transfu...

    G. E. G. Verhoef, P. Zachée, A. Ferrant, H. Demuynck, D. Selleslag… in Annals of Hematology (1992)

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    Myelodysplastic syndromes with bone marrow fibrosis: a myelodysplastic disorder with proliferative features

    We report on 22 patients with myelodysplastic syndrome (MDS), all of whom showed striking marrow fibrosis. Variable blood counts, often with teardrop poikilocytosis and a leukoerythroblastic picture, were pres...

    G. E. G. Verhoef, C. De Wolf-Peeters, A. Ferrant, S. Deprez… in Annals of Hematology (1991)

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    In vitro modulation of normal and diseased human neutrophil function by pentoxifylline

    The influence of pentoxifylline on normal and diseased neutrophil function has been studied in vitro. In high concentrations pentoxifylline stimulated human neutrophil chemotaxis toward both bacterial oligopep...

    M. A. Boogaerts, S. Malbrain, P. Meeus, L. van Hove, G. E. G. Verhoef in Blut (1990)