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    Article

    Gene–gene interactions in the NAMPT pathway, plasma visfatin/NAMPT levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy

    Nicotinamide phosphorybosil transferase (NAMPT) polymorphisms affect visfatin/NAMPT levels and may affect the responsiveness to therapy in hypertensive disorders of pregnancy. We examined whether NAMPT polymorphi...

    M R Luizon, A C T Palei, V A Belo, L M Amaral, R Lacchini in The Pharmacogenomics Journal (2017)

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    Article

    Tissue inhibitor of matrix metalloproteinase-1 polymorphism, plasma TIMP-1 levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy

    Tissue inhibitor of metalloproteinase (TIMP)-1 is a major endogenous inhibitor of matrix metalloproteinase (MMP)-9, which may affect the responsiveness to therapy in hypertensive disorders of pregnancy. We examin...

    M R Luizon, A C T Palei, V C Sandrim, L M Amaral in The Pharmacogenomics Journal (2014)

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    Article

    Polymorphisms of the adiponectin gene in gestational hypertension and pre-eclampsia

    Adiponectin is a hormone involved in energy homeostasis by regulating glucose and lipid metabolism. In addition, the adiponectin gene (ADIPOQ) has polymorphisms that can modulate the circulating concentration of ...

    J S R Machado, A C T Palei, L M Amaral, A C Bueno in Journal of Human Hypertension (2014)

  4. No Access

    Article

    Haptoglobin polymorphism affects nitric oxide bioavailability in preeclampsia

    Studies showed elevated cell-free hemoglobin (Hb) in preeclampsia (PE), and Hb reacts with nitric oxide (NO), decreasing its bioavailability. Haptoglobin (Hp) is a polymorphic protein (Hp1-1, Hp2-1 and Hp2-2) ...

    J T Sertório, R Lacchini, L M Amaral, A C T Palei in Journal of Human Hypertension (2013)

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    Article

    Assessment of oxidative status markers and NO bioavailability in hypertensive disorders of pregnancy

    The systemic oxidative status in hypertensives disorders of pregnancy (HDP) and its association with endothelial dysfunction is controversial. In the present study, we evaluated systemic plasma levels of oxida...

    H F Gomes, A C T Palei, J S R Machado, L M da Silva in Journal of Human Hypertension (2013)

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    Article

    Matrix metalloproteinase-9 polymorphisms affect plasma MMP-9 levels and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy

    Abnormal matrix metalloproteinase (MMP)-9 levels may have a role in hypertensive disorders of pregnancy. We examined whether MMP-9 genetic polymorphisms (g.−1562C>T and g.−90(CA)13−25) modify plasma MMP-9 and tis...

    A C T Palei, V C Sandrim, L M Amaral, J S R Machado in The Pharmacogenomics Journal (2012)

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    Article

    Maternal iNOS genetic polymorphisms and hypertensive disorders of pregnancy

    Increased expression and activity of inducible nitric oxide synthase (iNOS) may contribute to the pathogenesis of pre-eclampsia (PE) and gestational hypertension (GH). However, no previous study has examined w...

    L M Amaral, A C T Palei, V C Sandrim, M R Luizon in Journal of Human Hypertension (2012)

  8. Article

    1059 Body Composition of Adequate and Small for Gestational Age Newborns and the Relationship with Maternal Body Composition

    Introduction: Low birth weight and intrauterine growth restriction are associated to high morbidity and mortality. A compromised maternal nutritional status and placental failure could be responsible for intra...

    J S Camelo Jr, J P Monteiro, J S Marchini, E Ferriolli, K Pfrimer in Pediatric Research (2010)

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    Chapter and Conference Paper

    Corn and Soybean Residue Covers Effects on Wheat Productivity Under No-Tillage Practices

    Wheat (Triticum aestivumL.) grain yields under no-till production systems have been shown to be reduced in the presence of maize (Zea maysL.) residues. It has been suggested that sowing a greater density of wheat...

    M. Barraco, M. DÍaz-Zorita, G. Duarte in Wheat Production in Stressed Environments (2007)

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    Article

    The Hypothalamo-hypophyseal System of the White Seabream Diplodus Sargus: Immunocytochemical Identification of Arginine-vasotocin, Isotocin, Melanin-concentrating Hormone and Corticotropin-releasing Factor

    The distribution of the neurosecretory hormones vasotocin, isotocin and melanin-concentrating hormone and the hypophysio-tropic hormone corticotropin-releasing factor was studied in the hypothalamo-hypophyseal...

    G. Duarte, M.M. Segura-Noguera, M.P. Martín del Río in The Histochemical Journal (2001)